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AVITATreatment of Soft Tissue Reconstruction

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Acute full-thickness skin defects that require soft tissue reconstruction can include traumatic wounds such as abrasions and degloving, which is a type of injury where the skin is removed from the underlying tissue. Skin grafting is the standard of care for full-thickness, soft tissue reconstruction. In 2017, approximately 80% of acute wounds that required skin grafting were non-burn-related injuries accounting for more than 200,000 procedures in the U.S. Investigational research with the RECELL® System for the treatment of soft tissue reconstruction persists in the medical community.

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Enrollment has commenced in our trial evaluating the safety and effectiveness of the RECELL® System in combination with meshed autografting for patients undergoing reconstruction of skin defects not associated with a burn injury.

The study’s two primary effectiveness endpoints are:

  • Superior donor skin sparing, evaluated by comparing the actual expansion ratios (donor area to treated area) used in RECELL® treatment versus conventional autografting
  • Non-inferior incidence of healing by eight weeks post-treatment