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3D-Shaper Medical SL
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  5. 3d-Shaper - Dual-Energy X-ray ...

3d-Shaper - Dual-Energy X-ray Absorptiometry (DXA) Scan Software

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3D-SHAPER analyzes the proximal femur in 3D from a standard 2D Dual-energy X-ray absorptiometry (DXA) scan. It provides clinicians with a separate assessment of trabecular and cortical bone.

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computed tomography scanning
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femur
  • Automated workflow
  • Retrospective data analysis
  • Follow-up
  • Automated report generation
  • Embedded into a dedicated device
  • Connected to clinical center’s network or DXA computer
  • Compatible with most DXA scanners
  • 3D-SHAPER is not yet available for use in clinical practice in the USA.
  • Visualize the femoral shape and density in 3D
  • Measure the cortical surface density
  • Measure the volumetric trabecular density
  • Compare measurements with normative data
  • Monitor cortical and trabecular bone measurements

DXA is the gold standard technique used for the management and follow-up of osteoporosis. 3D-SHAPER is a software application that registers a 3D statistical model onto the hip DXA scan of the patient, and uses a model-based algorithm to create a 3D map of the cortical surface density. It allows clinicians to assess the cortical and trabecular macrostructure in 3D from a standard hip DXA scan.

Validation

A multicenter clinical study was performed to compare 3D-SHAPER with Quantitative Computed Tomography (QCT) analyses. Strong correlations were found between measurements performed using the two techniques [1].

Picture: Cortical thickness distribution (left) and frontal slices showing bone density values (right) obtained by 3D-SHAPER and QCT for three patients [1]

Algorithm

3D-SHAPER incorporates a statistical model built from a database of quantitative computed tomography scans. The shape and density variations in the first three principal directions are shown [1] .

3D-SHAPER registers the statistical model onto the DXA projection of the patient. The algorithm maximizes the similarity between the projection of the model and the DXA image [1] .
3D-SHAPER estimates the cortical thickness and density by the fitting a mathematical function onto the density profiles measured along the normal vector at each vertex of the femoral shape [2] .