Ovation - IBD Genomic and Clinical Linked Data Solutions
This Ovation IBD Genomic and Clinical Linked Data sample dataset is a packaged, real-world observational cohort of 10 Inflammatory Bowel Disease (IBD) subjects. It`s available at no cost for scientists interested in evaluating Ovation’s Whole Genome Sequencing and RNAseq data with up to 30x coverage. The data is linked with clinical data, including full redacted pathology reports, comorbidity diagnoses, therapeutic exposures, medical procedures, and surgical history. Also included is a Differential Gene Expression (DGE) analysis comparing gene expression on diseased and normal tissue from the same patients. *This sample dataset comes pre-packaged with WGS & RNAseq data linked to phenotypic data sourced by Ovation to provide an example turnkey solution. Although this dataset is linked using Datavant tokenization, it can be linked to almost any other phenotypic data that uses one of the commercially available tokenization technologies.
- IBD cohort of 212 patients genomes with option to sequence more on demand from our large IBD cohorts:
- Crohn’s: 2,651
- U. Colitis: 4,005
- Unspecified IBD: 16,880
- Deep IBD Omics data includes WGS (30X Depth, VCF Files) and RNA Seq from Normal & Diseased Tissue
- Datavant tokenization with existing linkage to phenotypic data including treatment exposure, comorbidities, lab value and disease severity metrics from claims and/or EHR
- Delivery of IBD cohort within 2 weeks of contracting
Top Medications
Mesalamine
Prednisone
Budesonide
Hydrocortisone
Picosulferate
Fluticasone
Adalimumab
Metronidazole
Omeprazole
Top Comorbidities
Diarrhea
Abdominal Pain
Other disease
of intestine
Hypertension
Anemia
Vitamin D
De ciency
Quicker access to genomic data from cohorts of interest
Our samples can be retrospectively sequenced and delivered in 90 days; faster than data could be prospectively captured and sequenced in clinical trials
Diverse US Coverage
Sourced from small labs across the country, Ovation data represents a diverse array of patients from racial and ethnic backgrounds.
Link to relevant phenotypic data
We can help your team link to a variety of data including claims, EHR, pathology and imaging with commonly used tokens and navigate difficult cohort creation and feasibility assessments for you.
Consent at every step
Testing samples are consented and de-identified for research purposes as part of the clinical workflow ensuring patient privacy and easy access to the data for your bioinformatics team.