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Targeted Multiplexed Protein Product Applications Available In Barbados
3 applications found
Several of the Navigo-created, ready-to-go Affilin molecules against solid tumor targets are currently developed as protein-drug conjugates (PDCs), by combining them to a half-life extending module and an engineered toxin-carrying moiety. Compared to notoriously difficult-to-produce and inhomogeneous Antibody-Drug Conjugates (ADCs), Affilin®-based PDCs have clear advantages. They are easily assembled from a specificity-conferring Affilin®, a half-life extending module and a toxin-carrying moiety. Each of ...
ByNavigo Proteins GmbH based in Halle, GERMANY
Solid tumor-specific Affilin molecules are currently being evaluated as CAR-T ligands. Specifically, they were confirmed to be functionally expressed on the effector cell surface, mediate target cell-binding and effective target cell-killing in a dose-dependent fashion. Importantly they were just as effective as commonly used antibody ...
ByNavigo Proteins GmbH based in Halle, GERMANY
Fluidity One-M by Fluidic Sciences Ltd. provides an innovative approach to studying membrane proteins without the need for traditional purification processes. This advanced instrument allows for analysis in-solution using single-use microfluidic channels, minimizing the risk of damaging delicate protein structures. It facilitates a more accurate study of protein conformation changes, ligand binding, and protein interactions in their native membrane environment. The instrument's smart assistant, Fluidity Insight, ...
ByFluidic Sciences Ltd based in Hertfordshire, UNITED KINGDOM