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42 applications found
However, as applications increasingly rely on ultra low variant allele frequency detection, NGS-based assays are beset with significantly more noise below 0.5% VAF that increases the rate of false positives. Laboratories looking to implement ctDNA assays need better quality controls that can ensure accurate detection and reporting by variant calling algorithms.Standardizing within patient measurements and across sites and platforms are equally critical to ensuring accurate ...
ByAccuGenomics, Inc. based in Wilmington, NORTH CAROLINA (USA)
Real-time Viral Titer Assay Capability. Current viral titer assay methods, a crucial component of vaccine & CGT development and production efforts, are generally slow, labor intensive, subjective, and difficult to standardize, often resulting in large errors or failures during critical production ...
ByLumaCyte, Inc. based in Charlottesville, VIRGINIA (USA)
Laser Force Cytology™ (LFC), rapid viral infectivity assay data correlates tightly with traditional plaque and TCID50 assays. ...
ByLumaCyte, Inc. based in Charlottesville, VIRGINIA (USA)
Providing physicians with innovative and meaningful assays for the earlier detection of clinically significantly prostate ...
ByMDxHealth based in Irvine, CALIFORNIA (USA)
A challenge to widespread adoption of RNASeq transcript abundance measurement for clinical studies and diagnostics is yield biases between targets affecting accuracy and reproducibility of the assay. Implementing a unique molecular index (UMI) approach can reduce bias, but at a cost of >8 fold increase in read ...
ByAccuGenomics, Inc. based in Wilmington, NORTH CAROLINA (USA)
Appearance ：white crystalline granule Assay： ≥98% PH： 5.0-8.0 Water： ≤1.5% It is used as a preservatives for coatings, slurries and to control microbial fouling in paper mills, oil field and leather process. ...
ByShandong Yubin Chemical Co.,Ltd based in Weifang, CHINA
Their activities have generally been established by specific cellular and molecular assays to determine mode of action. While frequently well tolerated, side-effects are nevertheless commonplace and can be the result of unexpected interference with unintended pathways in poorly understood ways. ...
ByCambridge Protein Arrays Ltd. (CPAP) based in Cambridge, UNITED KINGDOM
Clinical diagnostics as e.g. measurement of bacteria in urine with a luciferase based assay of bacterial ATP can be used in the diagnosis of urinary tract infection (UTI). Screening for Duchenne’s Muscular Dystrophy (DMD) has been performed in 528,410 newborn boys in a German study. Luciferase based assays of ATP and ATP+AMP is more and more used to control hospital hygiene. ...
ByBioThema AB based in Handen, SWEDEN
Partek tools enable you to start with raw data, detect amplified or deleted regions, and interpret or integrate the data with other assays such as gene expression. ...
ByPartek Incorporated based in Chesterfield, MISSOURI (USA)
Traditionally, in Single-Cell Force Spectroscopy (SCFS) assays, the object of interest is glued to an AFM cantilever resulting in complex handling and low throughput. ...
ByCytosurge AG based in Glattbrugg, SWITZERLAND
With Quasi Vivo, Kirkstall’s flow system, you can quickly and easily set up and run in vitro assays to detect hepatotoxicity of novel compounds. ...
ByKirkstall Ltd. based in York, UNITED KINGDOM
Tracking SARS-CoV-2 viral strain evolution is critical for monitoring new regional outbreaks, contact tracing, infection control and verifying the performance of front-line RT-PCR diagnostic assays. Being able to report accurate sequence variations confidently, is critically ...
ByAccuGenomics, Inc. based in Wilmington, NORTH CAROLINA (USA)
The concept behind protein arrays is the immobilisation of sets of proteins, up to very large numbers, on solid supports, to perform miniaturised, multiplexed binding assays with a variety of potential ligands or interactants (see powerpoint presentation on right). ...
ByCambridge Protein Arrays Ltd. (CPAP) based in Cambridge, UNITED KINGDOM
In recent years, however, many examples have come to light where poor validation of antibodies has led to misleading or erroneous conclusions for assays in which they are used as reagents, due to unrecognised cross-reactions and even a failure to react with their supposed target altogether. ...
ByCambridge Protein Arrays Ltd. (CPAP) based in Cambridge, UNITED KINGDOM
The Opto™ Cell Therapy Development workflow accelerates the creation of better therapeutics by performing multiple functional assays across 1,000s of individual T cells in a matter of days. Deeply characterize, profile, and map your T cell populations at the single-cell level to directly link phenotype to gene ...
ByBruker Corporation based in Billerica, MASSACHUSETTS (USA)
With products and services that can boost productivity, support regulatory compliance, and shorten time-to-market while ensuring high-quality assay results, Artel is helping BioPharma teams get ahead and stay ...
ByArtel, Inc. by Advanced Instruments based in Westbrook, MAINE (USA)
Radiance enhances the highly complex biomanufacturing process for cell therapies by providing new insights to cell therapy research and process development. Current process development assays are fraught with difficult and time-consuming steps requiring highly skilled scientists and bioengineers to produce these life saving treatments and ...
ByLumaCyte, Inc. based in Charlottesville, VIRGINIA (USA)
Methodology: The luc gene coding for firefly luciferase may be attached to another gene of interest. The expressing of this gene may then be estimated from the level of luciferase expression measured as light. This may be done in vitro, i.e. after lysing the cells adding ATP and D-luciferin, or in vivo. In the latter case D-luciferin has to enter the cells. Even whole live animals or plants may be studied, “in vivo imaging”, by injecting D-luciferin into the organism (ATP is already in the ...
ByBioThema AB based in Handen, SWEDEN
Combining the industry-standard Taqman assay with innovative engineering concepts, our XDive™ Superfast Real-Time PCR system can perform accurate pathogen detection, including the coronavirus, in as short as 5 minutes for 40 PCR cycles with no loss of sensitivity and ...
ByOnsiteGene Inc. based in San Diego, CALIFORNIA (USA)
Premium
Within the globalized pharmaceutical raw material supply chain, there is an increasing public health concern of raw material adulteration, contamination, or mislabeling, especially with recent incidents such as the adulteration of heparin. This has driven regulatory bodies to update their guidelines. Chapter 5.33 of the latest GMP guidelines for Medicinal Products for Human Use, provided by the European Commission (EC), entitled "Eudralex," specifies that "there should be appropriate procedures or measures to ...
ByGalaxy Scientific Inc based in Nashua, NEW HAMPSHIRE (USA)