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Gene Expressions Product Applications
17 applications found
Those events may be mirrored by changes in gene expression levels and are consequently involved in pathogenesis. Partek tools enable you to start with raw data, detect amplified or deleted regions, and interpret or integrate the data with other assays such as gene expression. ...
ByPartek Incorporated based in Chesterfield, MISSOURI (USA)
Gene expression is the most fundamental level at which the genotype gives rise to a phenotype. ...
ByPartek Incorporated based in Chesterfield, MISSOURI (USA)
Nucleic acid-protein interactions regulate many aspects of gene expression and thus cell physiology and pathology. DNA-protein interactions occur via a range of binding motifs present in transcription factors and nuclear receptors (e.g. DNA-binding domains, zinc fingers, leucine zippers) and histones and nonhistone proteins interacting with chromatin, all of which can influence gene expression. For RNA, hundreds of RNA binding proteins (RBPs) ...
ByCambridge Protein Arrays Ltd. (CPAP) based in Cambridge, UNITED KINGDOM
While many of the existing technologies rely on cell lysis — single-cell biopsy is the only non-invasive single-cell analysis method that allows researchers to take transcriptome snapshots of a cell without killing it. Gene expression profiles obtained from single-cell biopsies are suitable representations of lysed cell transcriptomes. ...
ByCytosurge AG based in Glattbrugg, SWITZERLAND
Deeply characterize, profile, and map your T cell populations at the single-cell level to directly link phenotype to gene ...
ByBruker Corporation based in Billerica, MASSACHUSETTS (USA)
Growth inhibition from e.g. antibiotics can be measured. Gene expression can be monitored. Please have a look at the application listing below to navigate to the product that matches your need. ...
ByBioThema AB based in Handen, SWEDEN
Isolating edited-pluripotent stem cells with traditional sorting techniques can subject the cells to rough conditions in which gene expression, genomic stability and overall cell-health can become compromised. ...
ByNanoCellect Biomedical, Inc. based in San Diego, CALIFORNIA (USA)
BOC Sciences is committed to supplying cost-effective products and services. We provide Peretinoin (Cas No:81485-25-8). More information, please visit the website: http://www.bocsci.com/peretinoin-cas-81485-25-8-item-84-305467.html ...
ByBOC Sciences based in Shirley, NEW YORK (USA)
BOC Sciences is committed to supplying cost-effective products and services. We provide Halofuginone (Cas No:55837-20-2). More information, please visit the website: http://www.bocsci.com/halofuginone-cas-55837-20-2-item-84-71625.html ...
ByBOC Sciences based in Shirley, NEW YORK (USA)
Methodology: The luc gene coding for firefly luciferase may be attached to another gene of interest. The expressing of this gene may then be estimated from the level of luciferase expression measured as light. ...
ByBioThema AB based in Handen, SWEDEN
For many years, researchers have investigated cell and gene therapies as potential replacement therapies for severe chronic diseases. Despite major advancements in the field, these approaches carry a number of limitations including immune rejection, limited eligibility, durability and variability challenges, inability to re-dose and high manufacturing costs. To address these drawbacks, we developed our novel Shielded Living Therapeutics™ (SLTx) platform, which we believe has the potential to result in ...
ByEli Lilly and Company based in Indianapolis, INDIANA (USA)
Single cell RNA-Seq is revolutionizing the study of complex tissues and diseases. The powerful and easy-to-use tools in Partek® Flow® empower researchers to analyze their own single cell RNA-Seq ...
ByPartek Incorporated based in Chesterfield, MISSOURI (USA)
Tumor markers found in blood, urine and body tissues can be used in diagnosing and treating cancer. Each tumor marker is indicative of a particular disease and thus can be used for the screening, monitoring and diagnosis of specific tumor types. In addition to being used in prognosis, these molecular markers help to predict the response, resistance and toxicity to therapy. For example, BCR-ABL gene sequence detection is used to diagnose chronic myelogenous leukemia and acute lymphatic ...
ByAurora Biomed Inc. based in Vancouver, BRITISH COLUMBIA (CANADA)
With Quasi Vivo, Kirkstall’s flow system, you can quickly and easily set up and run in vitro assays to detect hepatotoxicity of novel compounds. ...
ByKirkstall Ltd. based in York, UNITED KINGDOM
Generating cell lines has often been inefficient and affected by inaccurate limited dilution methods or the shear stress caused by conventional flow cytometer and traditional high-pressure cell sorters. NanoCellect Biomedical provides cell sorting solutions that allow to sort cells and establish stable cell lines using gentle low-pressure microfluidics. The WOLF’s ability to protect cell viability after sorting makes it an integral part of any cell line development workflow such as: Recombinant protein ...
ByNanoCellect Biomedical, Inc. based in San Diego, CALIFORNIA (USA)
Sample preparation is a significant yet underappreciated step that allows for high quality sequencing and analysis, critical to achieving breakthroughs in medicine, agriculture, and other industries. NanoCellect’s microfluidic cell sorter, the WOLF, allow the cell’s integrity to be maintained for numerous sequencing and multi-omics techniques. The WOLF’s ability to flexibly fit into any genomic researcher’s lab, make it a key step to any cell sequencing analysis workflow. 10x Genomics ...
ByNanoCellect Biomedical, Inc. based in San Diego, CALIFORNIA (USA)
Increase clinical translation with Organ-Chips for ADME-Tox assessments. Accurate ADME-Tox profiling of preclinical drug candidates remains a challenge. Preclinical ADME-Tox (Absorption, Distribution, Metabolism, Excretion, and Toxicity) studies are pivotal to predicting human response. However, approximately 30% of drugs fail during human clinical trials due to adverse reactions despite promising preclinical study results, and another 60% fail due to lack of efficacy. As companies broaden the modality toolbox ...
ByEmulate based in Boston, MASSACHUSETTS (USA)