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Gene Mutation And Expression Product Applications Available In Palau
7 applications found
Methodology: The luc gene coding for firefly luciferase may be attached to another gene of interest. The expressing of this gene may then be estimated from the level of luciferase expression measured as light. This may be done in vitro, i.e. after lysing the cells adding ATP and D-luciferin, or in vivo. In the latter case D-luciferin has to enter the cells. Even whole live animals or plants may be studied, “in vivo imaging”, by injecting D-luciferin into the organism (ATP is already in the ...
ByBioThema AB based in Handen, SWEDEN
Introducing single-cell biopsy The novel non-invasive method for single-cell omics The novel method that keeps your cells alive during biopsy from single cells Single-cell omics addresses cellular heterogeneity head on by isolating and analyzing molecular components from individual cells. While many of the existing technologies rely on cell lysis — single-cell biopsy is the only non-invasive single-cell analysis method that allows researchers to take transcriptome snapshots of a ...
ByCytosurge AG based in Glattbrugg, SWITZERLAND
Tumor markers found in blood, urine and body tissues can be used in diagnosing and treating cancer. Each tumor marker is indicative of a particular disease and thus can be used for the screening, monitoring and diagnosis of specific tumor types. In addition to being used in prognosis, these molecular markers help to predict the response, resistance and toxicity to therapy. For example, BCR-ABL gene sequence detection is used to diagnose chronic myelogenous leukemia and acute lymphatic ...
ByAurora Biomed Inc. based in Vancouver, BRITISH COLUMBIA (CANADA)
With Quasi Vivo, Kirkstall’s flow system, you can quickly and easily set up and run in vitro assays to detect hepatotoxicity of novel compounds. ...
ByKirkstall Ltd. based in York, UNITED KINGDOM
Deliver the right cells to the patient on time. Maximize Functional Characterization of Your Precious T Cell Samples. The Opto™ Cell Therapy Development workflow accelerates the creation of better therapeutics by performing multiple functional assays across 1,000s of individual T cells in a matter of days. Deeply characterize, profile, and map your T cell populations at the single-cell level to directly link phenotype to gene ...
ByBruker Corporation based in Billerica, MASSACHUSETTS (USA)
In the development of new drugs high throughput screening (HTS) is often used to screen large libraries of compounds for inhibitors or stimulators of various reactions. The firefly luciferase reaction can be performed reliably in a small reaction volume and is therefore highly suitable for HTS. Our Protein Kinase Kit RR can be used to measure not only protein kinase, but also all ATPases and aminoacyl tRNA synthetases. Growth inhibition from e.g. antibiotics can be measured. Gene expression can be monitored. ...
ByBioThema AB based in Handen, SWEDEN
Increase clinical translation with Organ-Chips for ADME-Tox assessments. Accurate ADME-Tox profiling of preclinical drug candidates remains a challenge. Preclinical ADME-Tox (Absorption, Distribution, Metabolism, Excretion, and Toxicity) studies are pivotal to predicting human response. However, approximately 30% of drugs fail during human clinical trials due to adverse reactions despite promising preclinical study results, and another 60% fail due to lack of efficacy. As companies broaden the modality toolbox ...
ByEmulate based in Boston, MASSACHUSETTS (USA)