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Targeted Boron Drugs Product Applications In Europe
4 applications found
Explore interaction profiles and identify off-target binding. Most drugs in common use are small organic molecules which interact functionally with proteins, either acting as ligands for receptors, inhibiting enzymes or blocking protein interactions, etc. Their activities have generally been established by specific cellular and molecular assays to determine mode of action. While frequently well tolerated, side-effects are nevertheless commonplace and can be the result of unexpected interference with unintended ...
ByCambridge Protein Arrays Ltd. (CPAP) based in Cambridge, UNITED KINGDOM
Functional ultrasound (fUS) imaging is emerging as a powerful tool in neuropharmacology to study the effects of drugs on brain activity. Unlike fMRI, fUS offers increased sensitivity and compatibility with awake animal models, providing an unbiased view of drug interactions with neural substrates. Recent studies by Theranexus have utilized fUS to observe the hemodynamic response to different pharmacological interventions, such as the combination of donepezil and mefloquine, which target acetylcholinesterase ...
ByIconeus based in Paris, FRANCE
In this example, the aggregation of magnetic nanoparticles labeled with DiR is monitored in real time. Tumor microvasculature is labeled using ...
ByMauna Kea Technologies based in Paris, FRANCE
Fluidity One-M by Fluidic Sciences Ltd. provides an innovative approach to studying membrane proteins without the need for traditional purification processes. This advanced instrument allows for analysis in-solution using single-use microfluidic channels, minimizing the risk of damaging delicate protein structures. It facilitates a more accurate study of protein conformation changes, ligand binding, and protein interactions in their native membrane environment. The instrument's smart assistant, Fluidity Insight, ...
ByFluidic Sciences Ltd based in Hertfordshire, UNITED KINGDOM