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Tumor Glycan Targeted Product Applications In Germany
3 applications found
Several of the Navigo-created, ready-to-go Affilin molecules against solid tumor targets are currently developed as protein-drug conjugates (PDCs), by combining them to a half-life extending module and an engineered toxin-carrying moiety. Compared to notoriously difficult-to-produce and inhomogeneous Antibody-Drug Conjugates (ADCs), Affilin®-based PDCs have clear advantages. They are easily assembled from a specificity-conferring Affilin®, a half-life extending module and a toxin-carrying moiety. Each of ...
ByNavigo Proteins GmbH based in Halle, GERMANY
The long-standing, successful use of radio-theranostics in imaging and therapy is based on targeting radiolabeled molecules to tumors or other diseased tissues. Over 10,000 hospitals worldwide use radioisotopes for in-vivo diagnosis or treatment, reaching around 35 million patients each year. The ideal cancer imaging tool is a homogenous conjugate with a precisely defined payload-to-carrier ratio, showing specific tumor-targeting with minimal side-effects and fast ...
ByNavigo Proteins GmbH based in Halle, GERMANY
Peptides and peptidomimetics constitute excellent tumor-specific targeting moieties and can be coupled to therapeutic and diagnostic radioisotopes via a linker and a ...
By3B Pharmaceuticals GmbH based in Berlin, GERMANY