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Immune Response Product Applications Near Malta
29 applications found
High-throughput analysis of immune repertoires has contributed to the elucidation of mechanistic underpinnings of autoimmunity, driving the development of novel therapies and better ...
ByEnpicom B.V. based in s-Hertogenbosch, NETHERLANDS
Antigens can be carried by liposomes, either lipids, proteins, DNA or RNA. They can also be combined with bacteria or virus components to form archaeosomes or virosomes, respectively. These vaccines have been proved to be effective in inducing immune responses and providing a sustained exposure to the antigen. More than 30 clinical trials are currently using liposomes for vaccine delivery including HIV and several types of ...
ByNanovex Biotechnologies based in Llanera, SPAIN
Determining adverse immune responses to monoclonal ...
ByAlcyomics Ltd. based in Newcastle Upon Tyne, UNITED KINGDOM
No single preventive health intervention is more cost-effective than immunization. Immune repertoire analysis has taken a predominant role in the development of vaccination strategies against infectious disease and has enabled characterization of the immune response against pathogens at high ...
ByEnpicom B.V. based in s-Hertogenbosch, NETHERLANDS
For many years, researchers have investigated cell and gene therapies as potential replacement therapies for severe chronic diseases. Despite major advancements in the field, these approaches carry a number of limitations including immune rejection, limited eligibility, durability and variability challenges, inability to re-dose and high manufacturing costs. To address these drawbacks, we developed our novel Shielded Living Therapeutics™ (SLTx) platform, which we believe has the potential to result in ...
ByEli Lilly and Company based in Indianapolis, INDIANA (USA)
We have developed proprietary methods for expressing immunotherapeutic payloads in a highly controlled and specific manner within tumors. IFN-α is a well-known therapeutic that was previously administered systemically for treatment of various cancers but it is currently rarely used because of its systemic toxicity. In the tumor microenvironment, IFN-α exerts its anti-tumor activity both directly by promoting cancer cell apoptosis and inhibiting vascularization and indirectly by restoring anti-tumor ...
ByGenenta Science based in Milano, ITALY
Downregulating the immune response is necessary for the treatment of autoimmune diseases. In this aspect, the APO2L/TRAIL ligand is a key intermediate in immune cascades and is secreted in exosomes in natural conditions. Its alteration has been associated with rheumatoid arthritis. The administration of synthetic exosomes decorated with APO2L/TRAIL has been shown to be effective in reducing the hyperplasia and overall inflammation in this ...
ByNanovex Biotechnologies based in Llanera, SPAIN
A defective gastrointestinal (GI) barrier is associated with multiple conditions of high unmet need, including inflammatory bowel disease, chemotherapy-induced gut injury, food allergies, and celiac disease. We are advancing novel, oral, non-immunosuppressive therapeutics to improve GI barrier function. Our multi-targeted approach involves improving epithelial cell homeostasis, restoring appropriate immune responses, and repairing secretory cell ...
ByKallyope Inc. based in New York City, NEW YORK (USA)
Natural killer (NK) cells have long been known to play a significant role in the body’s innate immune response. They were first described in the 1970s, but only in the last 15 years has significant progress been made in understanding the complexities and therapeutic potential these cells offer in helping fight cancer and other diseases. Today, we know that NK cells not only detect and identify malignant cancer cells, but they also induce cancer cell death and even help trigger a broader adaptive immune ...
ByKiadis Pharma NV based in Amsterdam, NETHERLANDS
EDS is an invaluable technique providing elemental composition information in direct relation to the Electron Microscope image for both Scanning Electron Microscopes (SEM) and Transmission Electron Microscopes (TEM). RaySpec has a wealth of experience in the design and manufacture of energy dispersive x-ray detectors used for EDS (Energy Dispersive Spectroscopy) on both SEMs and ...
ByRayspec Ltd. based in Buckinghamshire, UNITED KINGDOM
Inside the hyperbaric chamber, a user will absorb oxygen close to four times the normal breathing ...
ByOXYHELP INDUSTRY based in Bucuresti, ROMANIA
Dysregulation of immune cell functions can result in many serious and fatal diseases that require re-modulating the immune cells and restoring their normal response. Monitoring of immune cells while interacting with self-cells, pathogens, and cancer promotes our understanding of immune response or its failure ...
ByTelight based in Brno, CZECH REPUBLIC
Longitudinal imaging of pancreatic cancer. Monitor in a minimally invasive manner both tissue morphology and fibrosis (fluorescein) and cathepsin activity (Prosense® 680). A very thin probe (S 650) was used to monitor the pancreas of the same mouse over 9 months. ...
ByMauna Kea Technologies based in Paris, FRANCE
Unlike conventional vaccination strategies, cancer vaccines are designed to mount responses against tumor-specific antigens, arising from somatic mutations specific to the cancer genome. They promise a highly tailored approach by targeting patient-specific ...
ByEnpicom B.V. based in s-Hertogenbosch, NETHERLANDS
FluidFM® for Virology - Get a unique control over your single virion-single cell in-vitro experiment! Typically, viral infections are studied in bulk experiments where many cells in culture are exposed to the virus simultaneously, making it difficult to study single virus entry events or the spread of the viral infection between individual cells. With the gentle, micro-channeled, and force feedback-controlled FluidFM Probes, single virions can be deposited onto selected cells allowing unprecedented control to ...
ByCytosurge AG based in Glattbrugg, SWITZERLAND
Influenza, commonly known as “the flu”, is an infectious disease caused by an influenza virus that is spread by droplet transmission through the air from coughs and sneezes or by touching surfaces contaminated with the virus. Symptoms can be mild to severe with the most common including a high fever, runny nose, sore throat, muscle pains, headache, coughing, and feeling tired. These symptoms typically begin two days after exposure to the virus and most last less than a week. More severe complications ...
ByFluGen, Inc. based in Madison, WISCONSIN (USA)
2A Pharma’s vaccine platform is based on mutated parvoviral particles consisting essentially of one protein. The particles contain no viral genome and are replicative defective and non-pathogenic. The particle capsid surface has repetitive, immunogenic sites, where peptides of interest can be inserted and allows us to generate monovalent or bivalent vaccines as required. Each peptide of interest will be presented 60 times on the capsid surface and both the innate and adaptive immune systems are activated to ...
By2A Pharma ApS based in Aalborg Øst, DENMARK
Fluidity One-M by Fluidic Sciences Ltd. provides an innovative approach to studying membrane proteins without the need for traditional purification processes. This advanced instrument allows for analysis in-solution using single-use microfluidic channels, minimizing the risk of damaging delicate protein structures. It facilitates a more accurate study of protein conformation changes, ligand binding, and protein interactions in their native membrane environment. The instrument's smart assistant, Fluidity Insight, ...
ByFluidic Sciences Ltd based in Hertfordshire, UNITED KINGDOM
To date, the classification of cancers has been based solely on the phenotypic and genotypic characteristics of tumor cells. A new paradigm, scientifically well established and recommended by WHO guidelines, relies on the introduction of the immune response as a new prognostic parameter to predict and refine the clinical outcomes of cancer patients. Maximize patient survival rates with an assessment of the tumor immune response. ...
ByVeracyte based in Marseille Cedex 9, FRANCE
The increase or decrease of a natural immune response to obtain a therapeutic result is the basis of immunotherapy. It holds great promise for the treatment of autoimmune diseases, cancer, and the prevention of transplant ...
ByNanovex Biotechnologies based in Llanera, SPAIN