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Hormonal Production Articles & Analysis

8 articles found

How Lipid Metabolism Fuels Steroid Hormones and Why Their Analysis Matters

How Lipid Metabolism Fuels Steroid Hormones and Why Their Analysis Matters

Lipids, often simply thought of as fats, play a far more complex and vital role in our bodies than just energy storage. They are fundamental building blocks for cell membranes, crucial for nutrient absorption, and, significantly, the precursors to a powerful class of signaling molecules: steroid hormones. Understanding the deep connection between Lipid Metabolism and these hormones, along with ...

ByCreative Proteomics


Exploring the Thyroid-Stimulating Hormone (TSH): Master Regulator of Thyroid Function

Exploring the Thyroid-Stimulating Hormone (TSH): Master Regulator of Thyroid Function

Introduction of TSH The Thyroid-Stimulating Hormone (TSH) protein is a crucial player in the regulation of thyroid function. In this blog post, we will explore the structure, function, and significance of TSH in maintaining a healthy thyroid. Structure of TSH Let's start by understanding the structure and function of TSH. TSH, also known as thyrotropin, is a glycoprotein hormone secreted by ...

ByCreative BioMart


Rani Therapeutics offers breakthrough capsule for patients with chronic conditions

Rani Therapeutics offers breakthrough capsule for patients with chronic conditions

Rani Therapeutics offers a breakthrough capsule, the RaniPill which could change the way patients with chronic conditions take medication by eliminating the need for painful injections. Rani Therapeutics is a clinical-stage biotherapeutics company offering an alternative to painful injections for patients with chronic conditions such as neuroendocrine tumours(NETS). The company based in ...

ByRani Therapeutics


Fertility Clinics and Egg Freezing: Nitrogen Use and How to Remain Safe

Fertility Clinics and Egg Freezing: Nitrogen Use and How to Remain Safe

For women who want to have children when the time is right, egg freezing is a viable option and one that has become more popular in recent years. As an abundance of fertility clinics pop up nationwide, it is important to consider the safety implications of IVF, egg freezing, and fertility clinics. Dive into the world of fertility clinics to understand how eggs remain viable -- sometimes for years ...

ByPureAire Monitoring Systems, Inc


Tissue explant co‐culture model of the hypothalamic‐pituitary‐gonadal‐liver axis of the fathead minnow (Pimephales promelas) as a predictive tool for endocrine disruption

Tissue explant co‐culture model of the hypothalamic‐pituitary‐gonadal‐liver axis of the fathead minnow (Pimephales promelas) as a predictive tool for endocrine disruption

Endocrine disrupting compounds (EDCs) can impact the reproductive system by interfering with the hypothalamic‐pituitary‐gonadal (HPG) axis. While in vitro testing methods have been developed to screen chemicals for endocrine disruption, extrapolation of in vitro response to in vivo action shows inconsistent accuracy. We describe here our tissue co‐culture of the fathead minnow (Pimephales ...

ByJohn Wiley & Sons, Ltd.


Effects of progesterone and norethindrone on female fathead minnow (Pimephales promelas) steroidogenesis

Effects of progesterone and norethindrone on female fathead minnow (Pimephales promelas) steroidogenesis

As knowledge of contaminants capable of adversely modulating endocrine functions increases, attention is focused on the effects of synthetic progestins as environmental endocrine disrupters. In the present study, effects of exposure to a synthetic progestin (norethindrone, 168 ± 7.5 ng/L) and endogenous progestogen (progesterone, 34 ± 4.1 ng/L) on steroidogenesis in adult female fathead minnows ...

ByJohn Wiley & Sons, Ltd.


Endocrine disruption and reproduction impairment in zebrafish after long‐term exposure to DE‐71

Endocrine disruption and reproduction impairment in zebrafish after long‐term exposure to DE‐71

Our objective was to investigate the impact of Polybrominated diphenyl ethers (PBDEs) on fish reproduction over two generations. Zebrafish (Danio rerio) embryos (F0) were exposed to low concentrations (3, 10, 30 μg/L) of the PBDE mixture DE‐71 until they were sexually mature, and steroid hormone production, expression of genes involved in steroidogenesis, gonadal development and gamete ...

ByJohn Wiley & Sons, Ltd.


Endocrine disrupting, mutagenic, and teratogenic effects of upper Danube River sediments using effect‐directed analysis

Endocrine disrupting, mutagenic, and teratogenic effects of upper Danube River sediments using effect‐directed analysis

Effect‐directed analysis (EDA) can be useful in identifying and evaluating potential toxic chemicals in matrixes. Previous investigations of extracts of sediments from the upper Danube River in Germany revealed acute nonspecific and mechanism‐specific toxicity as determined by several bioassays. In the present study, EDA was used to further characterize these sediments and identify groups of ...

ByJohn Wiley & Sons, Ltd.

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