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Tumor Samples Articles & Analysis
9 articles found
In this white paper, Predictive Oncology (POAI) highlights a recent successful project in partnership with the University of Michigan Natural Products Discovery Core (NPDC) through the ACE program. The ACE program supports academic researchers in their early drug discovery and development initiatives by providing access to the POAI proprietary active machine learning platform and ...
Discover how matched tumor-normal sequencing can help clinical researchers detect the somatic origin of variants with certainty. In the era of precision oncology, it has become increasingly common for patients diagnosed with cancer to undergo tumor sequencing. Identifying the mutations that make up a tumor’s genomic landscape can help guide selection of targeted therapies and inform ...
In epigenomics experiments, the use of parallel samples is to ensure the reliability and repeatability of experimental results. The choice of the number of parallel samples depends on various factors, including experimental design, expected variability, data analysis methods, etc. Here are some specific examples to illustrate the selection of the number of parallel samples in different ...
This white paper details a study by Predictive Oncology and UPMC Magee-Womens Hospital. By combining the assets and domain expertise of both organizations, this collaboration aimed to improve ovarian cancer prognosis and treatment through accurate patient stratification and survival outcome predictions. Background and objective High grade serous carcinoma (HGSC) of the ovary is a complex and ...
An article on the rapid identification of pediatric brain tumors using DMS was published in Frontiers in Oncology, section Neuro-Oncology and Neurosurgical Oncology! The results show that most common pediatric brain tumor samples can be differentiated with DMS. DMS shows promise in becoming and additional instrument for real-time diagnosis of brain tumors. (The header image for this post ...
Introduction Genomics has revolutionized cancer research, transforming the way we diagnose, treat, and monitor cancer. Among the powerful genetic analysis methods, Whole Exome Sequencing (WES) stands out as a cutting-edge technique that employs sequence capture technology to enrich DNA from the whole exome regions, enabling high-throughput sequencing. WES offers a simpler, more cost-effective, ...
Purpose The incidence and mortality rates of cervical cancer are declining in the United States; however, worldwide, cervical cancer is still one of the leading causes of death in women, second only to breast cancer. This disparity is at least partially explained by the absence of or comparatively ineffective screening programs in the developing world. Recent advances in expression genomics have ...
The use of tumour markers to diagnose, assess prognosis, and select a suitable cancer treatment has become possible due to the development of inexpensive and user-friendly molecular analysis tools such as the polymerase chain reaction (PCR). Maintaining the integrity of biomarkers during their processing and storage is therefore of critical importance to accurately diagnose and give prognosis ...
Multiple myeloma is an essentially incurable plasma cell cancer with a very poor prognosis for patients; however, in a recent study published in Science Translational Medicine entitled "Selective targeting of multiple myeloma cells with a monoclonal antibody recognizing the protein CD98 heavy chain," scientists from Osaka University in Japan have discovered the CD98 heavy chain, a common ...