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Arterial Disease Articles & Analysis
24 articles found
Structure of Matrix Metalloproteinase (MMP) Family In vertebrates, the MMP family consists of 28 members, at least 23 of which are expressed in human tissues, 14 of which are expressed in the vascular system. MMPs are usually classified into collagenases, gelatinases, stromelysins, matrilysins, membrane-type (MT)-MMPs, and other MMPs based on their substrates and the organization of their ...
Heart failure affects about 6.2 million Americans and is rising in prevalence. With half of these cases presenting as heart failure with preserved ejection fraction (HFpEF), it’s essential for both the medical community and the population at large to have a better understanding of its pathology. [1,2] Knowing the differences between HFpEF and its counterpart, heart failure with reduced ...
Overview What is HFpEF? Heart failure with preserved ejection fraction (HFpEF) is a clinical syndrome in which patients have signs and symptoms of HF as the result of high left ventricular (LV) filling pressure, despite normal or near-normal LV ejection fraction (EF). Most patients with HFpEF also display normal LV volumes and an abnormal diastolic filling pattern (i.e, diastolic ...
Start-up Alucent Biomedical is using a light-activated molecule, delivered via a balloon catheter, to create a natural vascular scaffold in diseased peripheral vessels, with the aim of providing a long-lasting treatment option that maintains patency while leaving nothing behind in the vessel. Alucent Biomedical Inc. is rethinking peripheral artery disease (PAD) treatment with a novel natural ...
Patient History Patient presented with a history of hypertension, hyperlipidemia, peripheral arterial disease, obesity, arterial fibrillation, and transient ischemic attack. Patient had total knee replacement surgery and developed a complication due to improper off-loading, developing pressure ulcer on the right heel. Patient was treated with collagen products and wet to dry dressings prior to ...
A cyclo-ergometer exercise test was performed on this 57-year old male patient. He is a smoker with a family background of CAD. He is suffering from left bundle branch block making ST-segment analysis impossible. The patient has achieved 78 % of max. heart rate at 120 watts. Moderate paleness and dyspnoea have been observed at the end of the 120 watts step. However, after a normal initial ...
Pathophysiology, treatment options and hot topics Improvements In Stemi Treatment The immediate and long-term prognosis of patients experiencing an ST segment elevation myocardial infarction (STEMI) has changed dramatically since the introduction of coronary reperfusion therapies during primary percutaneous coronary intervention (pPCI). The evolution of these therapies accelerated with the ...
By not taking care of your teeth there is more on the line than tooth decay and periodontal disease – although that’s bad enough. Practicing good oral hygiene may be lifesaving according to a number of research studies.Studies show a connection between Gum disease and a 63% HIgher Pancreatic Cancer in Men The link between several systemic illnesses including diabetes, heart disease, ...
Dental Problems Linked To Heart Disease and Diabetes Over the last ten years there has been a growing body of evidence linking periodontal disease and systemic diseases. Every day new research is making the link stronger. Periodontal infection is the advanced stages of gum disease that causes bone loss. The bone loss is irreversible. Gingivitis is the early stage of gum disease and with early ...
Before a patient can get fit with their multi-articulating myoelectric hand, it’s vital that their prosthetist conducts a thorough evaluation and understands the cause of amputation or limb loss. This information helps prosthetists understand what a patient’s needs are so they can determine which prosthetic hand is the best fit for them. With this in mind, we’ll discuss the ...
Abstract Objective: Vascular conduit is essential for arterial reconstruction for a number of conditions, including trauma and atherosclerotic occlusive disease. We have developed a tissue-engineered human acellular vessel (HAV) that can be manufactured, stored on site at hospitals, and be immediately available for arterial vascular reconstruction. Although the HAV is acellular when implanted, ...
ABSTRACT: The incidence of wartime vascular injury has increased and is a leading cause of mortality and morbidity. While ligation remains an option, current resuscitation and damage control techniques have resulted in vascular repair being pursued in more than half of wartime injuries. Options for vascular reconstruction are currently limited to autologous vein or synthetic conduits, choices ...
ABILITY Diabetes Global (Randomized Comparison of Abluminus DES+ Sirolimus-Eluting Stents versus Everolimus-Eluting Stents in Coronary Artery Disease Patients with Diabetes Mellitus Global) started off with the index patient enrolment on 11th June 2020 in Italy (at the peak of the 1st wave of COVID-19 pandemic) by P.I. Prof. Antonio Colombo and the pace of enrolment since then has been steady and ...
Every year, surgeons perform a lower-limb amputation due specifically to diabetes on approximately 73,000 patients in the US alone. Annually there are over 1 million limb amputations worldwide. Most of these amputations are performed for the treatment of non-healing diabetic foot ulcers that resulted from PAD (Peripheral Arterial Disease). These non-healing foot ulcers are caused by high blood ...
As we begin this New Year we have an opportunity to begin with a fresh start as we pursue our passion to promote and speed the healing of wounds! Our role as Wound Care Clinicians has risen to a whole new level of essential care for an extremely high risk population. In this current Covid-19 climate that we are living in, we are all facing challenges that we have never dealt with before. ...
While heart attack, cardiac arrest and heart failure can sometimes be related, they’re actually three very different types of cardiac emergencies. Cardiac arrest, heart attack and heart failure — three terms that are familiar to most people, but often get confused with one another. While there can be some overlap between them in terms of cause and effect, they are actually three ...
Cardiovascular diseases (CVDs) cause 17 million deaths globally every year, making it the leading cause of death around the world. The cardiovascular system—which includes your heart and blood vessels—distributes oxygen through the body and removes waste. Every cell in the body depends on this process to run smoothly. Your cardiovascular system plays a key role in your overall ...
Amsterdam, the Netherlands – Royal Philips (NYSE: PHG; AEX: PHIA), a global leader in health technology, today announced that it has signed an agreement to acquire Vesper Medical Inc., a US-based medical technology company that develops minimally-invasive peripheral vascular devices. Vesper Medical will further expand Philips’ portfolio of diagnostic and therapeutic devices ...
Abstract Background. As the most advanced stage of peripheral arterial disease (PAD), chronic limb-threatening ischemia (CLTI) is associated with a high risk of lower-limb loss and mortality. Percutaneous deep vein arterialization (pDVA) is a promising new treatment alternative for CLTI patients who cannot be treated with conventional revascularization techniques. Our study objective was to ...
What interested you in LimFlow, and how did you get involved in the PROMISE I trial? Dr. Clair: Practicing vascular surgery, where a number of patients are evaluated for chronic limb-threatening ischemia (CLTI), you are guaranteed to have patients who are not candidates for percutaneous or surgical revascularization. These patients often have arterial systems open or identifiable to the ankle, ...