Mammalian Cell Engineering Articles & Analysis
2 articles found
Rare diseases collectively affect hundreds of millions of people worldwide, yet many individual conditions remain difficult to diagnose and treat due to their low prevalence and complex biological mechanisms. In recent decades, therapeutic enzymes have emerged as an important class of biologic drugs that address the underlying causes of several rare genetic disorders. By replacing or ...
Stable cell lines are the preferred expression systems for producing recombinant proteins, especially for producing large, complex proteins with post-translational modifications. The most common mammalian cell line used for recombinant protein production is the Chinese hamster ovary (CHO) cell line. A large portion of recombinant biopharmaceutical proteins is involved in utilizing CHO-based cell ...