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Advanced Sequencing Articles & Analysis
82 articles found
The modification of tRNA methylation is essential for controlling the cell cycle in tumor cells. The rapid advancement of high-throughput sequencing technology has enabled scientists to identify and report numerous tRNA methylation modifications and their modifying enzymes which control cell cycle regulation. ...
This approach provides a broader genomic view than targeted bisulfite sequencing while requiring significantly less sequencing depth. Forensic Fragment Analysis In forensic applications, HindII generates highly discriminative restriction fragment length polymorphisms from genomic DNA. ...
This approach provides a broader genomic view than targeted bisulfite sequencing while requiring significantly less sequencing depth. Forensic Fragment Analysis In forensic applications, HindII generates highly discriminative restriction fragment length polymorphisms from genomic DNA. ...
Acting as chemoattractant molecules, chemokines are central to both innate and adaptive immunity, influencing not only immune surveillance but also wound healing and angiogenesis. Over the past few decades, advancements in immunology and molecular biology have intensified the focus on chemokines, particularly recombinant chemokines, for their potential therapeutic and diagnostic ...
Alfa Cytology, a prominent services provider in oncology, has launched its cutting-edge ovarian cancer therapy development services. This significant advancement represents a vital leap in the quest for more precise and effective treatments for ovarian cancer. ...
Alfa Cytology unveils advanced cancer immunotherapy development services. Alfa Cytology, a renowned services supplier in oncology, has recently introduced its groundbreaking cancer immunotherapy development services. ...
The advent of next-generation sequencing (NGS) has revolutionized the field of microbiome research, particularly through the analysis of 16S rRNA gene sequencing. ...
In microbial research, OTUs are primarily utilized to analyze gene sequence datasets, particularly those derived from modern sequencing technologies. ...
Among these advancements, dual RNA sequencing (dual RNA-seq) stands out as a groundbreaking technique that facilitates simultaneous transcriptomic analysis of both the host and the pathogen during infection. ...
Next-Generation Sequencing (NGS) has revolutionized genomics, providing unprecedented insights into the structure and function of genomes, transcriptomes, and epigenomes. A critical step in the NGS workflow is library preparation, which involves converting DNA or RNA samples into a form that can be sequenced. NGS Library Preparation Kits play a pivotal role in this process, ensuring high-quality ...
Within the rapidly advancing realm of biotechnology, zebrafish genome editing services are carving a niche, heralding a new epoch in genomics and cellular research. ...
Mass spectrometry can accurately identify glycosylation sites, while Western blotting is used to detect the glycosylation status of specific proteins. With the advancement of technology, high-throughput sequencing and mass spectrometry technologies have become powerful tools for identifying and quantifying glycosylation sites. ...
Submission of sequence data to NCBI archives Next-generation sequencing, PacBio SMRT sequencing, and Nanopore sequencing, can generate numerous sequence data in a single run. Raw reads or assembled sequence need to be submitted to public sequence repository (DDBJ/ENA/GenBank - INSDC), which is required by the overwhelming majority of journals as accession numbers of theses sequence data should ...
Since the year 2000, the advent of massively parallel sequencing technologies has orchestrated a revolution in high-throughput sequencing capabilities. Critical breakthroughs, including pyrophosphate sequencing, reversible terminator chemical sequencing, and supported oligonucleotide ligation and sequencing, have ...
When a ribosome is affixed to the polypeptide (protein) it is making, the ribosome-nascent chain complex (RNC) is the compilation of molecules that make up the ribosome. One of several methods can be used to halt the synthesis of the nascent polypeptide. RNCs are made and purified in labs to study the dynamics, biochemistry, folding, and interactions that the ribosome and proteins undergoing ...
The backbone of clonality analysis is DNA and RNA sequencing, the most precise methods of determining the genetic makeup of cells. Through techniques such as next-generation sequencing (NGS), researchers can analyze huge volumes of genetic data, enabling the detection of even slight genetic variations among clones. ...
However, traditional methods of antibody discovery require substantial time and effort and often fail to identify the most effective antibodies. In recent years, the advancement of single-cell sequencing technologies has offered a new possibility for the screening of antibodies.What is Single-Cell Sequencing?Single-cell ...
Also, Protein-Protein Interaction Sequencing can be applied to drug target screening and effectiveness evaluation. ...
ESMO updated its recommendations for NGS in advanced cancers this year, urging broader use of NGS in additional cancer types and the inclusion of tumor-agnostic biomarkers. The ESMO Precision Medicine Working Group (PMWG) first published its recommendations for when to use next-generation sequencing (NGS) in routine practice for patients with metastatic ...
Proteins, peptides, and antibodies are important molecules in the body and are important objects of research in biopharmaceuticals and personalized medicine. With the continuous advancement of protein, peptide, and antibody sequencing technology, they are playing an increasingly important role in the medical field.Precision Medicine and Targeted TherapyThrough ...