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Biomarker Development Articles & Analysis
28 articles found
Autoimmune and Inflammatory Diseases: Cytokines are central to the development and progression of autoimmune and inflammatory diseases. Customized assays can help identify biomarkers and therapeutic targets. Drug Development: Evaluating the impact of new drugs on cytokine profiles is essential for assessing their efficacy and safety. ...
Understanding and analyzing these biomolecules has become increasingly important in areas such as disease research, biomarker discovery, and drug development. NAD and NADH are not merely passive participants in metabolism—they are regulatory molecules that influence key metabolic pathways, including glycolysis, oxidative phosphorylation, and biosynthetic ...
Additionally, multiplex cytokine analysis is a valuable tool in vaccine development and drug discovery, providing real-time feedback on immune modulation. ...
By analyzing these interactions, scientists can identify new biomarkers for disease, develop targeted therapies, or discover novel glycan-binding proteins with potential applications in drug design. 2. ...
Alfa Cytology has announced cancer diagnostic biomarker development services to enhance precision in oncology research. ...
Bioinformatics AnalysisBioinformatics tools and software can be used to predict potential glycosylation sites by identifying possible glycosylation sites by analyzing the features of protein or nucleic acid sequences.Glycosylation plays a key role in the development of many diseases. For example, in cancer, abnormal glycosylation patterns may lead to changes in protein function, ...
For specific acetylation site localization, mass spectrometry is usually the preferred method.Changes in the acetylation level of a specific protein are related to the development of various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. ...
Cancer is a daunting diagnosis; however, the rapid advancements in oncology are continuously perfecting patient outcomes and quality of life. Among the groundbreaking developments, cancer vaccines are a promising frontier1. These vaccines are transforming how we approach cancer treatment, leveraging the body's immune system to fight malignancies more effectively. ...
With professional knowledge of PC (particularly intra-tumor heterogeneity, TME crosstalk, and micro-environmental instability) and powerful cross-platform collaboration capability, Alfa Cytology has launched a series of PC vaccine development services to meet pre-clinical research needs. The PC vaccine development services at Alfa Cytology are more targeted ...
By analyzing the changes of lipid biomarkers throughout the disease process and their interactions with other biomolecules, we can grasp the position of lipid metabolism disorders in the development of diseases as a whole and identify the possible pathogenesis. ...
Individuals with germline mutations in the CDH1 gene have a significantly increased risk of developing HDGC. Understanding the mechanisms underlying CDH1 loss and its impact on cancer progression is crucial for developing targeted therapies and improving patient outcomes. ...
Its significance lies in its involvement in B cell development and activation, making it a valuable target for research and clinical applications. ...
Despite the skepticism surrounding its viability in a clinical setting, QSM shows great potential in a wide range of clinical applications, particularly for biomarker detection and ...
SubB2M is an engineered protein that specifically detects the pan-cancer biomarker Neu5Gc that is found at elevated levels in multiple human cancers. ...
Studies have shown that lncRNAs are quite complex in function and play an important role in various biological processes such as development, differentiation, proliferation, metastasis, apoptosis, stem cell pluripotency, and DNA damage. ...
Digital biomarkers can open a world of possibilities in understanding the nuances of a patient’s behavior and response to treatment. ...
ByAiCure
Glycans can serve as a source for the development of novel clinical biomarkers that provide a range of specific targets for therapeutic intervention. ...
Interleukin-17 (IL-17) IL-17 is an important soluble factor in the process of T-cell induction and promotion of inflammation. It promotes neutrophil development and maturation and stimulates the production of inflammatory transmitters such as IL-6, IL-8, granulocyte colony-stimulating factor and prostaglandin E2 (PGE2) by epithelial cells, endothelial cells, macrophages and ...
LONDON, June 28, 2021 (GLOBE NEWSWIRE) – Treos Bio Limited (“Treos”), a clinical stage biotechnology company using data science and proprietary biomarkers to develop precision off-the-shelf and personalized peptide cancer immunotherapies, today announced the publication of a peer-reviewed article titled “A Peptide Vaccine Candidate ...
Oncimmune’s ImmunoINSIGHTS can leverage the power of these antibodies – regarded as sentinels of the adaptive immune response to cancer – as prospective biomarkers in immunotherapy development programmes. Our work has demonstrated the ability of autoantibodies to help predict therapy outcomes, immune-related adverse events (irAEs) and immune ...