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Drug Platform Articles & Analysis

17 articles found

Human Astrocytes-Cerebellar (HA-c): A New Frontier in Neurobiology

Human Astrocytes-Cerebellar (HA-c): A New Frontier in Neurobiology

This allows for the investigation of disease progression and the exploration of potential therapeutic interventions. Drug Screening: HA-c provide an excellent platform for high-throughput drug screening. ...

ByCreative Bioarray


Introduction to 3D Printing Technology and Oral Thin Films

Introduction to 3D Printing Technology and Oral Thin Films

Additionally, 3D printing can address issues such as poor drug solubility and stability, thus broadening the range of drugs that can be effectively delivered through oral films. ...

ByCD Formulation


Exploring Mouse Luminex Cytokine Assays: A Powerful Tool for Immune Research   

Exploring Mouse Luminex Cytokine Assays: A Powerful Tool for Immune Research  

The Luminex Cytokine Assay is a multiplex platform that allows simultaneous detection and quantification of multiple cytokines, chemokines, and growth factors in a single sample. ...

ByCreative Proteomics


Alfa Cytology Introduces Advanced Drug Development Services for Brain Tumor

Alfa Cytology Introduces Advanced Drug Development Services for Brain Tumor

Alfa Cytology has introduced its advanced drug development services for brain tumors. Alfa Cytology, celebrated for its cutting-edge biotech solutions and extensive tumor research expertise, has recently introduced brain tumor drug development services, designed to empower researchers in understanding the intricacies and unique challenges associated with brain ...

ByAlfa Cytology


Nanoformulation Platform: A Beginner's Guide

Nanoformulation Platform: A Beginner's Guide

This cutting-edge technology has garnered significant attention from researchers and pharmaceutical companies alike, due to its potential to transform the way medications are formulated and administered. The nanoformulation platform embodies this innovative stride by providing a robust framework for engineering and delivering drugs at the nanoscale. ...

ByCD Formulation


The Liposome-Based PROTAC Strategy

The Liposome-Based PROTAC Strategy

The binding of folate molecules on the nanoparticle surface to folate receptors on cell surfaces allowed for more efficient cellular uptake of the drug, further increasing drug uptake within cells. Cell penetration experiments using flow cytometry confirmed the cell-selective uptake properties of the LipoSM-PROTAC platform, offering a new ...

ByBOC Sciences


Predicting cardiotoxicity with engineered 3D human cardiac tissue models

Predicting cardiotoxicity with engineered 3D human cardiac tissue models

Today operating in Madison, Wisconsin, the founders work with scientific advis­ers and collaborate with leading academic and government institutions. Drug Discovery Platform IVS has become a leading developer of human 3D cell and tissue culture models by providing a high-throughput, functional system for testing cardio safety and efficacy to screen and ...

ByInvivoSciences, Inc. (IVS)


Using AI to Fight a Pandemic: Insilico Medicine Announces Novel Preclinical Candidate for COVID-19 Treatment

Using AI to Fight a Pandemic: Insilico Medicine Announces Novel Preclinical Candidate for COVID-19 Treatment

Insilico Medicine announced the nomination of a novel preclinical therapeutic candidate for treating COVID-19, designed using the generative chemistry AI platform Chemistry42. The new drug candidate is a 3CL protease inhibitor unique from existing drugs in its class because it can be rapidly produced. ...

ByInsilico Medicine


In Silico Development of Combinatorial Therapeutic Approaches Targeting Key Signaling Pathways in Metabolic Syndrome

In Silico Development of Combinatorial Therapeutic Approaches Targeting Key Signaling Pathways in Metabolic Syndrome

Drug development platform, BIOiSIMâ„¢, was used to narrow down two different drug classes with distinct modes of action and modalities. ...

ByVeriSIM Life


How much do animal models play a role in drug development?   

How much do animal models play a role in drug development?  

Published by Vijay K Singh and Thomas M Seed on September 3, 2021, in Expert Opinion on Drug Discovery and deals with the necessity of animal models for modern drug research in the direction of animal strains, animal models, requirements, and pathways for developing new drugs. ...

ByCreative Biolabs


Investigation into the Feasibility of a 2 mL Needle-Free Injector

Investigation into the Feasibility of a 2 mL Needle-Free Injector

Having already demonstrated in our PRECISE II saline self-injection study that our needle-free drug delivery platform is preferred more than 8 to 1 (78% v. 9%) to a prefilled syringe amongst healthy volunteers and injects with less self-reported pain, we sought to further explore our platform’s potential with a 2 mL injection. ...

ByPortal Instruments, Inc.


A hybrid modeling approach for assessing mechanistic models of small molecule partitioning in vivo using a machine learning integrated modeling platform

A hybrid modeling approach for assessing mechanistic models of small molecule partitioning in vivo using a machine learning integrated modeling platform

Prediction of the first-in-human dosing regimens is a critical step in drug development and requires accurate quantitation of drug distribution. ...

ByVeriSIM Life


Increasing the Efficiency of Drug Development with Preclinical Testing Using Human Intestinal Stem Cells

Increasing the Efficiency of Drug Development with Preclinical Testing Using Human Intestinal Stem Cells

A new drug lacking that liability or with a reduced liability would be very attractive. ...

ByAltis Biosystems


Evaluating Microbiome Therapies with Intestinal Cell Models

Evaluating Microbiome Therapies with Intestinal Cell Models

The obvious first step in this endeavor was the development of platforms based on primary human epithelial stem cells that can be used for drug screening. ...

ByAltis Biosystems


Looking to the Future of Neuro Devices: Exclusive Interview with Alcyone Lifesciences CEO PJ Anand

Looking to the Future of Neuro Devices: Exclusive Interview with Alcyone Lifesciences CEO PJ Anand

Alcyone Lifesciences is a medical technology company based out of Lowell, MA, which specializes in central nervous system (CNS) drug delivery platforms for targeted infusions of the brain or spinal cord. ...

ByAnuncia Medical, Inc.


The Five Factors of Smart Laboratory Success

The Five Factors of Smart Laboratory Success

They were comfortable with this approach, but this made this critical data hard to find, hard to understand and hard to reuse by the modellers who wanted to introduce better modelling into the drug pipeline. An innovative information platform to capture, integrate, manage and analyse in vivo experimental data in a much more coherent fashion was commissioned and ...

ByTessella Support Services plc


Nanopharmaceuticals I: nanocarrier systems in drug delivery

Nanopharmaceuticals I: nanocarrier systems in drug delivery

To achieve maximum pharmacological effects with minimum side effects of drugs, drugs should be delivered to target sites without significant distribution to non-target areas. Using pharmaceutical nanocarrier systems for drug delivery is a useful delivery platform for improving target specificity, therapeutic activity, and ...

ByInderscience Publishers

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