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Genome Structural Articles & Analysis
18 articles found
Fosmid libraries represent a pivotal advancement in the field of genomics and molecular biology, offering a robust method for genomic cloning and analysis. ...
Next-Generation Sequencing (NGS) has revolutionized genomics, providing unprecedented insights into the structure and function of genomes, transcriptomes, and epigenomes. ...
The detailed point is to sequence the unknown genome sequence, and use bioinformatics analysis means to splice and assemble the sequence, so as to obtain the map of its genome. ...
Prediction of Functional and Structural Domains Identifying known functional or structural domains using databases and tools (such as Pfam, SMART, InterPro, etc.). ...
Many rare diseases have obvious manifestations of chromosomal structural abnormalities, making it a strategy to determine the cause of diseases from a macroscopic perspective of genetics. ...
What is pan-genome? A pan-genome is the sum of all genomic information within a species. With the development of genomic technology, researchers have found that a single reference genome can no longer meet the needs of genomic data analysis, and more and more species, including the human ...
HCoVs are categorized into four genera depending on sequence comparisons of viral genomes: alpha, beta, gamma, and delta coronaviruses. SARS-CoV-2 is a genetically linked beta coronavirus of another bat coronavirus named BatCoV RaTG13 and SARS-CoV-1. ...
Overview of Whole Genome Sequencing The genome of each individual organism contains its entire genetic information. ...
In addition to often invading the respiratory system, it can also infringe on the reproductive system, nervous system, conjunctiva and embryos. FHV-1 Genome Structure and Encoded Glycoproteins FHV-1 is a double-stranded DNA virus with an envelope. The full genome sequence is 126-134 kbp, and the GC content in the base is about 50%. Its ...
They are generally divided into fungi, actinomycetes, bacteria, spirulina, rickettsia, chlamydia, mycoplasma and viruses. Microbial whole genome sequencing is an important tool for mapping genomes of novel organisms, finishing genomes of known organisms, or comparing genomes across multiple samples. Sequencing the entire ...
Based on long-read sequencing technology, whole human genome sequencing can accurately develop the genetic variation of DNA sequences between samples and reference genome or between individuals, such as structural variation (SV) and copy number variation (CNV), by using the obtained 10~20kb long reads to compare with the reference ...
Long read sequencing has great application in the direction of de novo genome sequencing and resequencing, especially to improve the accuracy of detecting repeat regions, structural variants, as well as complex regions. Researchers used long read sequencing to produce haploid human genome assembly, populating multiple gaps in the reference ...
There is an insightful technical report by Innophore, summarizing information about the coronavirus: its structure, active sites, sequence data, and so on. While showing similarities to beta coronaviruses found in bats, the specific coronavirus behind the COVID-19 pandemic is genetically different from other coronaviruses such as the previously known Middle East respiratory ...
Genome initiatives spearheaded by burgeoning numbers of data custodians such as Genomics England (GEL), a Lifebit customer, leverage technological advances to amass large volumes of patient data. ...
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Fully finished genomes Roughly one-tenth of the human genome remained uncharted when genomics researchers Karen Miga at the University of California, Santa Cruz, and Adam Phillippy at the National Human Genome Research Institute in Bethesda, Maryland, launched the Telomere-to-Telomere (T2T) consortium in 2019. ...
Second, cellular machinery translates AAV’s viral genome into proteins which assemble into a viable viral shell with a copy of the viral genome packaged inside it. ...
Ontologies are used in service matching and dynamic web service composition, and are heavily used in bioinformatics and genomics to characterise the structure of living things. Our research focuses on complexity metrics for ontologies. ...
Morphologically, P335 resembled the L. lactis phages TP901-1 and Tuc2009, except for a shorter tail and a different collar/whisker structure. Its 33,613-bp double-stranded DNA genome had 50 open reading frames. Putative functions were assigned to 29 of them. Unlike other sequenced genomes from lactococcal phages belonging to this species, P335 ...
