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Hematologic Cancer Articles & Analysis

8 articles found

In Vivo CAR-T Therapy: From Concept to Clinical Momentum

In Vivo CAR-T Therapy: From Concept to Clinical Momentum

CAR-T cell therapy has transformed the treatment landscape for hematological cancers, yet its widespread adoption remains limited by the complexity of ex vivo manufacturing. ...

ByBiopharma PEG Scientific Inc


ADC Cleavable Linker : Classification and Mechanism of Action

ADC Cleavable Linker : Classification and Mechanism of Action

Antibody-drug conjugates (ADCs), as emerging anticancer drugs, can deliver highly cytotoxic molecules directly to cancer cells to kill them. ADC is a monoclonal antibody covalently bound to cytotoxic chemical substances (payload) through linker. ...

ByBOC Sciences


Autoimmune Diseases Targets

Autoimmune Diseases Targets

In addition to its indirect effects, TSLP can directly act on CD4+ T cells, aiding in their proliferation, differentiation, and response to antigens[3]. TSLP and cancer New functions of TSLP have been discovered in the induction and progression of various tumors, including solid tumors such as breast, colon, and pancreatic cancers, as well as ...

ByBeta Lifescience


Clinical Pharmacology of Antibody-Drug Conjugates

Clinical Pharmacology of Antibody-Drug Conjugates

In general, the incidence of ADA of ADCs is less in patients targeting hematologic cancer than in patients targeting solid cancer; Most ADA is specific to the monoclonal antibody domain of the ADC. ...

ByBOC Sciences


A Novel Potential Target for CAR-T Cell Therapy in Human Solid Tumors Discovered

A Novel Potential Target for CAR-T Cell Therapy in Human Solid Tumors Discovered

At present, chimeric antigen receptor T cell therapy (CAR-T) has made significant achievements in the treatment of specific hematological cancers, allowing patients with relapsed/refractory disease to survive longer and become healthier, but in clinical studies, cell therapy has actually not been successful in the treatment of patients with solid tumors, in part ...

ByCreative BioMart


Israeli hospital pilots rapid diagnostics of blood cancer with Sight Diagnostics

Israeli hospital pilots rapid diagnostics of blood cancer with Sight Diagnostics

Israeli-founded firm Sight Diagnostics, the company that uses AI and cutting-edge hardware to deliver rapid, complete blood count results, has signed a new research agreement with Jerusalem’s Shaare Zedek Medical Center to identify the possibility of blood cancer using a combination of images and data collected from Sight’s OLO device and patient clinical information ...

BySight Diagnostics


Detailed Introduction to Clinical Significance of Amylase

Detailed Introduction to Clinical Significance of Amylase

Malignant tumors Many malignant tumors can cause elevated serum amylase, the most common are ovarian cancer, lung cancer and multiple myeloma. Ectopic synthesis of tumor tissue is the cause of this phenomenon. ...

ByCreative Enzymes


Remote Oncology Care: Review of Current Technology and Future Directions

Remote Oncology Care: Review of Current Technology and Future Directions

Visits to cancer clinics and hospitals risk exposing immunocompromised patients to infectious complications. ...

ByPAVmed Inc.

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