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Immune Modulation Articles & Analysis

26 articles found

BIOPHARMA PEG Showcases DSPE-PEG-Mannose: A Cutting-Edge Polymer for Drug Delivery and Biomedical Applications

BIOPHARMA PEG Showcases DSPE-PEG-Mannose: A Cutting-Edge Polymer for Drug Delivery and Biomedical Applications

Encapsulating anticancer drugs within its lipid bilayer improves drug accumulation in target tissues while reducing toxicity to healthy cells.Immunomodulatory TherapyFunctionalized DSPE-PEG-Mannose nanoparticles can modulate immune responses by interacting with mannose receptors on immune cells, contributing to novel treatments for ...

ByBiopharma PEG Scientific Inc


Immunotoxicology Services: Understanding the Foundation of Immune System Safety

Immunotoxicology Services: Understanding the Foundation of Immune System Safety

In vitro testing involves studying immune responses in controlled laboratory environments using cell cultures. ...

ByCreative Bioarray


Understanding Luminex Cytokine Panels and Their Role in Multiplex Cytokine Analysis   

Understanding Luminex Cytokine Panels and Their Role in Multiplex Cytokine Analysis  

Cytokines and growth factors are essential signaling molecules that play pivotal roles in immune regulation, inflammation, tissue repair, and numerous physiological and pathological processes. ...

ByCreative Proteomics


Advancements in mRNA Delivery: A New Era in Therapeutics

Advancements in mRNA Delivery: A New Era in Therapeutics

Each of these platforms offers unique advantages, such as enhanced stability, targeted delivery, and reduced immune responses, making them promising candidates for future mRNA therapeutics. ...

ByCreative Biogene


Unveiling the Power of Immune Receptor Stable Cell Lines in Immunological Research

Unveiling the Power of Immune Receptor Stable Cell Lines in Immunological Research

Immune receptors, which are protein molecules expressed on the membrane of immune cells, play a key role in regulating immune responses. ...

ByCreative Biogene


The Vital and Complex Role of Elastase

The Vital and Complex Role of Elastase

This digestive form of elastase is essential for the proper metabolism of proteins in our diet. In the immune system, elastase produced by neutrophils plays a key role in defense mechanisms. ...

ByCreative Enzymes


Cytokine Profiling in Oncology: The Power of Luminex Technology   

Cytokine Profiling in Oncology: The Power of Luminex Technology  

Cancer is a complex disease that involves a delicate interplay between the tumor cells and the host immune system. Cytokines play a critical role in this interplay, mediating the communication between different cells of the immune system and modulating immune responses. ...

ByCreative Proteomics


The Role of Cytokine Profiling in Oncology Research

The Role of Cytokine Profiling in Oncology Research

Cancer is a complex disease that involves a delicate interplay between the tumor cells and the host immune system. Cytokines play a critical role in this interplay, mediating the communication between different cells of the immune system and modulating immune responses. ...

ByCreative Proteomics


Mechanisms to Combat Drug Resistance: Overview of Antimicrobial Peptides

Mechanisms to Combat Drug Resistance: Overview of Antimicrobial Peptides

These peptides play a crucial role in the innate immune system's defense against microbial infections, exhibiting antimicrobial properties that can inhibit the growth or kill bacteria, fungi, viruses, and even some parasites. ...

ByBOC Sciences


Unveiling the Role of CD73: A Key Player in Immune Regulation and Beyon

Unveiling the Role of CD73: A Key Player in Immune Regulation and Beyon

Its primary function revolves around converting extracellular ATP into immunosuppressive adenosine, working in tandem with CD39 within normal tissues to curtail excessive immune reactions. However, this mechanism is often hijacked by tumors, utilizing CD73 to foster an adenosinergic process that shields them from immune assaults. ...

ByBeta Lifescience


CADM: A New Generation of Tumor Suppressor Genes

CADM: A New Generation of Tumor Suppressor Genes

CADM molecules, particularly CADM1, have been implicated in tumor immune escape due to their involvement in immune cell interactions and regulation of immune responses. ...

ByBeta Lifescience


Ozette’s computationally-driven analysis aids advancement of cancer drug development - Case study

Ozette’s computationally-driven analysis aids advancement of cancer drug development - Case study

Pairing high parameter flow cytometry with Ozette’s next generation analysis helped decipher the complex immune landscape of tumors and revealed tumor-specific cell populations that modulate immune responses. ...

ByOzette Technologies


Leishmaniasis Vaccine - Case Study

Leishmaniasis Vaccine - Case Study

The World Health Organization in its report on Neglected Tropical Diseases has stated that there is overwhelming evidence to show that the burden caused by many of the 17 diseases that affect more than 1 billion people worldwide can be effectively controlled and, in many cases, eliminated or even eradicated. Leishmaniasis caused by Leishmania spp is one such example and poses a grave health risk ...

ByPAI Life Sciences


Cytokine Storms and Viral Infections

Cytokine Storms and Viral Infections

Cytokines function in autocrine, paracrine or endocrine forms, and can regulate cell growth and differentiation, modulate immune response and participate in the development of various diseases such as inflammation by binding to the corresponding receptors. ...

ByCreative Proteomics


RVx201 Herpes Vaccine

RVx201 Herpes Vaccine

Unfortunately, ICP0 also aids the virus in evading the immune system's protective defenses, namely the interferon-mediated response. ...

ByRational Vaccines, Inc.


A "miracle" fruit that can enhance the immune response to tumors   

A "miracle" fruit that can enhance the immune response to tumors  

The advent of immune checkpoint inhibitors (ICI) has improved the overall survival of patients with a variety of malignancies. ...

ByCreative Biolabs


ELife: T Interferon Suppresses Inflammatory Diseases by Balancing the Microbiome

ELife: T Interferon Suppresses Inflammatory Diseases by Balancing the Microbiome

The maintenance of immune homeostasis involves a synergistic relationship between the host and the microbiome. ...

ByCreative BioMart


Q&A with Brian Saputro, R&D Scientist at Regeneus

Q&A with Brian Saputro, R&D Scientist at Regeneus

Regeneus was one of the first in the industry to identify the role of the secretome in modulating the immune system, contributing to addressing patient symptoms, but also to the disease modifying effects. ...

ByRegeneus Ltd.


Overcoming Immunological Challenges Limiting Capsid-Mediated Gene Therapy With Machine Learning

Overcoming Immunological Challenges Limiting Capsid-Mediated Gene Therapy With Machine Learning

The challenges of evading both pre-existing immunity and de novo adaptive immune responses against AAV vectors are made especially difficult by the heterogeneous nature of patient immune responses and immune histories. Thus, discovering capsids that circumvent the immune system is a significant hurdle facing ...

ByDyno Therapeutics


Alleviation of DSS-induced colitis via Lactobacillus acidophilus treatment in mice

Alleviation of DSS-induced colitis via Lactobacillus acidophilus treatment in mice

Abstract Gut microbiota play a major role in host physiology and immunity. Inflammatory bowel diseases (IBDs), the important immune-related diseases, can occur through immune system malfunction originating due to dysregulation of the gut microbiota. ...

ByKoBioLabs

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