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In Vitro Analysis Articles & Analysis
7 articles found
RDC Binding Analysis ServiceRDC Binding Analysis Service evaluates how well the drug binds to its target receptors or tissues. ...
One essential approach to studying cellular metabolism is Metabolic Flux Analysis (MFA), a powerful tool that reveals the intracellular activities and metabolic dynamics of living systems. ...
Our GFP-LC3, GFP-LC3 Control Mutant, and RFP-LC3 lentiviral particles provide bright fluorescence and precise localization of LC3 to the autophagosome, enabling live cell analysis of autophagy even in difficult-to-transfect cell types. Features Improved biosensor expression efficiency with lentiviral transduction Ability to transfect dividing, non-dividing, and ...
We have successfully identified small molecule antagonists against PCSK9 through a virtual screen coupled with in vitro and cell-based assays. Our lead compound, P-4, exhibited a concentration-dependent inhibition of the PCSK9/LDLR interaction with an IC50 in the nanomolar range, an increase in the level of LDLR in recombinant cell-based assays, and a significant increase in the ...
The authors conducted a comprehensive analysis of cross‐species comparability of chemical–ERα interactions based on information concerning structural attributes of estrogen receptors, in vitro binding and transactivation data for ERα, and the effects of a range of chemicals on estrogen‐signaling pathways in vivo. Overall, this integrated analysis ...
In the present study, we sought to provide an in‐depth characterization of WF metabolism in birds using in vivo and in vitro approaches. We performed a kinetic analysis of WF metabolism using liver microsomes of four avian species and found that the metabolic ability of the chicken and crow are much higher in comparison to the mallard and ostrich. ...
Health care waste consists of solid, liquid and gaseous waste contaminated with organic and inorganic substance including pathogenic radionuclide generated from in vitro analysis of body microorganisms. Hospital waste possesses serious tissues and fluid. ...