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In Vitro Tissue Articles & Analysis

7 articles found

Science Bake Off - Engineers Use Soda Bread In Tissue Engineering

Science Bake Off - Engineers Use Soda Bread In Tissue Engineering

Summary Scientists were not immune to the home baking trends that grew out of a year of self-isolation and working from home. A creative application of soda bread as scaffolding for tissue engineering produced some exciting results and highlights the value of keeping it ...

BySterlitech Corporation


A hybrid modeling approach for assessing mechanistic models of small molecule partitioning in vivo using a machine learning integrated modeling platform

A hybrid modeling approach for assessing mechanistic models of small molecule partitioning in vivo using a machine learning integrated modeling platform

While VDss shows distribution of the drug compounds between plasma and tissues, it does not count differences of tissue composition and morphology. ...

ByVeriSIM Life


3D Bioprinting Of Prevascularised Implants For The Repair Of Critically-Sized Bone Defects

3D Bioprinting Of Prevascularised Implants For The Repair Of Critically-Sized Bone Defects

The aim of this study was to develop a bioprinting strategy to engineer prevascularised tissues in vitro and to investigate the capacity of such constructs to enhance the vascularisation and regeneration of large bone defects in vivo. ...

ByRegenhu


Enhancing Human Gut Tissue Models through Gene Editing

Enhancing Human Gut Tissue Models through Gene Editing

Many Challenges Around Accessing Tissues Disease modeling provides the best results when actual human tissues are used. ...

ByAltis Biosystems


Evaluating Microbiome Therapies with Intestinal Cell Models

Evaluating Microbiome Therapies with Intestinal Cell Models

Screening a prebiotic, probiotic, or a compound or drug against only one type of cell will not provide the entire picture of what occurs in the human intestine, therefore, a complex and complete in vitro tissue model comprising all the different cell types found in the human intestine and colon is desirable and more physiologic. ...

ByAltis Biosystems


	 A human in vitro three-dimensional bioprinted liver tissue system can be used to model nutritional damage and protective effects of MSDC-0602K, a novel modulator of the mitochondrial pyruvate carrier (MPC)

A human in vitro three-dimensional bioprinted liver tissue system can be used to model nutritional damage and protective effects of MSDC-0602K, a novel modulator of the mitochondrial pyruvate carrier (MPC)

Diet-induced disease using a three-dimensional multicellular human tissue model provides the potential to reconstruct the effects of overnutrition in vitro and to potentially model the actions of an agent like MSDC-0602K. ...

ByOrganovo Holdings Inc.


Effects of progesterone and norethindrone on female fathead minnow (Pimephales promelas) steroidogenesis

Effects of progesterone and norethindrone on female fathead minnow (Pimephales promelas) steroidogenesis

In vivo exposure to either compound lowered expression (nonsignificant) of luteinizing hormone (LHβ) levels in the brain along with significantly down‐regulating the beta isoform of membrane progesterone receptor (mPRβ) in ovary tissue. The correspondence between lowered LHβ levels in the brain and mPRβ in the ovary is suggestive of a possible functional association as positive ...

ByJohn Wiley & Sons, Ltd.

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