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Inflammatory Factor Articles & Analysis
13 articles found
Th17 and Treg cells, two novel subsets of CD4+ T cells, have become a hot topic of research in the regulation of inflammatory responses. It has been found that the development of myasthenia gravis (MG), multiple sclerosis (MS) and Guillain-Barré syndrome (GBS) is associated with abnormalities of Th17 and Treg cells and cytokines and transcription factors. ...
Functionally, TREM1 acts as an amplifier of inflammatory responses. Upon activation, it potentiates the production of pro-inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-α), interleukin-1 beta (IL-1β), and interleukin-6 (IL-6), thereby exacerbating the inflammatory cascade. ...
However, an excessive immune response can be harmful to the organism itself. The inflammatory response is an important active defense mechanism of the body, but chronic inflammation is one of the predisposing factors for cancer development. ...
Cytokines in Cytokine Release Syndrome (CRS) CRS, a systemic inflammatory reaction stemming from diverse triggers such as infections, autoimmune inflammation, and medical causes, involves various cytokine classes including inflammatory effectors, initiators, modulators, chemokines, and colony-stimulating factors. ...
Inflammation and Immune Responses: Some Ig-superfamily CADMs are involved in inflammatory responses, guiding leukocytes (white blood cells) to sites of inflammation or injury. ...
As the name suggests, TSLP was initially identified in the mouse thymic stromal cell line Z210R, as a factor that promotes the proliferation and development of immature B cells. Subsequently, TSLP was found to function as a co-stimulatory factor for thymic cell proliferation and as a lymphopoietin[1]. Although the homology between human and mouse TSLP is low, ...
The above mentioned systemic inflammatory markers reflect the main risk factors for the development of macrovascular complications that lead to a significant increase in morbidity and mortality. ...
Cytokines are classified according to their different roles in the inflammatory response: pro-inflammatory cytokines and anti-inflammatory cytokines. ...
TME contains various cytokines, chemokines, growth factors, inflammatory mediators, and matrix remodeling enzymes to promote communications among the cells that make up TME. ...
Non-surgical Periodontal Therapy Dental plaque is known as the principal etiologic factor for the inflammatory periodontal disease; therefore, it is evident that treatment of the disease is dependent upon how much the plaque and its retentive factors are being removed. ...
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The incidence rates of ALDs are strongly affected by several risk factors such as the quantity and pattern of alcohol consumption, gender, ethnicity, diet, and host genetic factors (O'Shea et al., 2010, Stickel and Hampe, 2012). ...
What is autoimmune disease? Autoimmune disease a condition in which the body’s immune system mistakenly attacks the body itself. Thus far, more than 80 different autoimmune diseases have been identified, with some of the most prevalent including rheumatoid arthritis, Crohn’s disease, type 1 diabetes, and multiple sclerosis [1]. Autoimmune disease is one of the top ten causes of ...
Clearance of apoptotic cells by a membrane PS receptor is one of the critical anti-inflammatory functions of macrophages. However, the PS binding receptors and their recognition mechanisms have not been fully investigated. Recently, we reported that stabilin-2 is a PS receptor that mediates the clearance of apoptotic cells, thus releasing the anti-inflammatory ...