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Lipid System Articles & Analysis

15 articles found

In Vivo CAR-T Therapy: From Concept to Clinical Momentum

In Vivo CAR-T Therapy: From Concept to Clinical Momentum

The acquisition highlighted growing industry confidence in: In vivo immune cell engineering mRNA-based therapeutic platforms Advanced lipid nanoparticle delivery systems Rather than focusing on a single asset, the deal underscored the strategic value of the delivery platform itself. Delivery Systems as the Key Enabler At the core of in vivo ...

ByBiopharma PEG Scientific Inc


Lipid Nanodiscs: A New “Circular” Force in Drug Delivery

Lipid Nanodiscs: A New “Circular” Force in Drug Delivery

However, a new kind of drug delivery system has also gradually emerged in recent years: lipid nanodiscs (LNDs). With their unique "flat disc" structure and excellent performance, they are also regarded as a new and promising drug delivery system. In a word, lipid nanodiscs can be simply imagined as a microscopic ...

ByCD Bioparticles


Exploring Traditional and Innovative Techniques in Lipid Synthesis

Exploring Traditional and Innovative Techniques in Lipid Synthesis

This method is particularly appealing for large-scale production, as biological systems can often yield high quantities of specific lipids with natural stereochemistry. ...

ByBOC Sciences


Exosome Lipidomics and Metabolomics: A New Frontier in Disease Diagnosis and Therapy

Exosome Lipidomics and Metabolomics: A New Frontier in Disease Diagnosis and Therapy

The Importance of Exosome Lipidomics and Metabolomics The term lipidomics refers to the study of lipids in biological systems, whereas metabolomics involves the profiling of metabolites, the small molecules generated during metabolic processes. ...

ByCreative Biostructure


The Role of Natural Lipids in Promoting Optimal Health

The Role of Natural Lipids in Promoting Optimal Health

What are Natural Lipids?Natural lipids are organic compounds that are insoluble in water but soluble in organic solvents. ...

ByMatexcel


Nanoparticle Development: Revolutionizing Drug Delivery Systems

Nanoparticle Development: Revolutionizing Drug Delivery Systems

In this article, we will explore different types of nanoparticle development that are revolutionizing drug delivery systems. Polymer Nanoparticles for Drug Delivery Polymer nanoparticles are a popular choice for drug delivery systems due to their biocompatibility and versatility. ...

ByCD Formulation


How to Prepare Nano-vesicles for Encapsulating Protein Drugs?

How to Prepare Nano-vesicles for Encapsulating Protein Drugs?

Nano-vesicles, also known as liposomes, have emerged as promising drug delivery systems due to their unique structure and properties. These tiny spherical lipid bilayers can encapsulate various therapeutic agents, including protein drugs. ...

ByCD Formulation


Liposomes as Drug Delivery Vehicles

Liposomes as Drug Delivery Vehicles

Due to the amphiphilic nature of lipids in liposomes, they can serve as candidate vehicles for drug delivery, and liposomes have received more attention than other systems because of their remarkable ability to deliver drugs to their target sites. ...

ByCD Formulation


The Key Technology of RNA Therapy

The Key Technology of RNA Therapy

There are three main types of delivery systems in the market: nanoparticle delivery system, covalent coupling modification delivery system and exosome delivery system. ...

ByBOC Sciences


A hybrid modeling approach for assessing mechanistic models of small molecule partitioning in vivo using a machine learning integrated modeling platform

A hybrid modeling approach for assessing mechanistic models of small molecule partitioning in vivo using a machine learning integrated modeling platform

This theoretical phenomenon, i.e. the ability to infer the parameters of the biological system from the observed outputs/measurements is called identifiability25, 26. ...

ByVeriSIM Life


Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine

Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine

Despite this commonality, the physiological importance of lipid accumulation and whether this phenomenon can be recapitulated in experimental systems remain unknown. Lipid metabolism is critical for proper cellular function in all tissues. ...

ByJohnson Controls, Inc.


Nanopharmaceuticals I: nanocarrier systems in drug delivery

Nanopharmaceuticals I: nanocarrier systems in drug delivery

Using pharmaceutical nanocarrier systems for drug delivery is a useful delivery platform for improving target specificity, therapeutic activity, and reducing toxicity of drugs. Various sophisticated nanocarrier systems have been developed for drug delivery, and this review focuses on liposomes, polymeric nanoparticles, polymeric micelles, lipid ...

ByInderscience Publishers


Nanobiotechnology approaches for targeted delivery of pharmaceutics and cosmetics ingredients

Nanobiotechnology approaches for targeted delivery of pharmaceutics and cosmetics ingredients

Nanobiotechnology refers to the ability to create and manipulate biological and bio-chemical materials, devices, and systems at atomic and molecular levels. Nano delivery systems hold great potential to overcome some of the obstacles in bio-pharmaceutical production, such as water soluble/insoluble pharmaceutical drugs and cosmetic ingredients, risks of toxicity, ...

ByInderscience Publishers


Protection of gastrointestinal and haematopoietic systems by ascorbic acid-2-glucoside in mice exposed to whole-body gamma radiation

Protection of gastrointestinal and haematopoietic systems by ascorbic acid-2-glucoside in mice exposed to whole-body gamma radiation

Whole-body exposure of mice to gamma radiation leads to depletion of tissue antioxidant defence and damages the haematopoietic and gastrointestinal systems in mice. Administration of ascorbic acid-2-glucoside (AsAG) at a dose of 100 mg/kg body weight could prevent the radiation-induced reduction of total White Blood Cell (WBC) count and decrease in bone marrow viability following ...

ByInderscience Publishers


Regulation of cancer by therapeutic vaccination and dietary bio-modulation involving organ-specific mitochondria

Regulation of cancer by therapeutic vaccination and dietary bio-modulation involving organ-specific mitochondria

The importance of the biological control by lipids in the Central Nervous System (CNS) acting as the 'lipidome' in healing process is especially emphasised. ...

ByInderscience Publishers

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