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Malaria Articles & Analysis
27 articles found
Quinine, an alkaloid found in the bark of the cinchona tree (Cinchona officinalis), has historically been used in the treatment of malaria. Additionally, artemisinin, derived from the sweet wormwood plant (Artemisia annua), has gained attention for its potent antimalarial properties. ...
Additionally, alkaloids like cocaine have been used as local anesthetics for surgical procedures. l Antimalarial effect Alkaloids have emerged as promising candidates in the fight against malaria, displaying potent antimalarial effects. Artemisinin, an alkaloid extracted from Artemisia annua, revolutionized malaria treatment. Its remarkable efficacy against ...
One mRNA vaccine (MRNA-1345) also showed >80% protection in Phase III trials and has been granted a breakthrough therapy by the FDA. Non-viral pathogens such as malaria (57 species) and pneumococcus (40 species) also represent an important area. Conjugate vaccines are the main focus of pneumococcal vaccines, while recombinant proteins and viral vectors are the main platforms ...
In medicinal research, thiazoles and their derivatives have a variety of biological and pharmacological activities, such as antibacterial, anti-malaria, anti-cancer, anti-schizophrenia, anti-hypertension, anti-inflammatory, and anti-HIV. ...
Each year malaria kills hundreds of thousands of people – mostly children – around the globe, and according to a report by the WHO, in 2021 nearly half of the world’s population was at risk of malaria. ...
Scientists in the 1600s noted quinine’s effect against malaria. Malaria is a vector-borne disease caused by four parasites: Plasmodium falciparum, P. vivax, P. ovale, and P. malariae. ...
Quinine Quinine is a drug used to treat a variety of conditions, most notably malaria. It is listed as one of the WHO’s (World Health Organization’s) “Essential Medicines”. ...
Artemisinin Artemisinin is a widely used drug in the standard treatment of malaria. It is extracted from the plant Artemisia annua, sweet wormwood, but can also be produced in a semi-synthetic fashion. ...
The COVID-19 pandemic has placed health and wellbeing at the forefront of the global agenda, revealing an urgent need to strengthen healthcare systems and build capacity and preparedness for health emergencies as well as routine care. The pandemic has also underlined inequalities, raising significant questions around access to healthcare and healthy lifestyles for the most vulnerable in our ...
Multiplex real-time PCR: A guide to application In multiplex real-time PCR (qPCR), scientists amplify two or more target genes in the same reaction, using the same reagent mix. Multiplexing allows scientists to overcome limitations for myriad applications. First and foremost, multiplexing enables scientists to conserve valuable samples used in a quantitative assay, which is especially ...
The SOLIDARITY trial will seek to repurpose currently available drugs, evaluating the experimental antiviral remdesivir, the malaria drugs chloroquine and hydroxychloroquine, a combination of the HIV drugs lopinavir and ritonavir, and lopinavir—ritonavir plus interferon beta. ...
Malaria. Yellow Fever. Zika. Dengue. West Nile virus. These are some of the diseases, carried by mosquitos, that infect millions of people worldwide every year. ...
Among the listed medicinal plants, the greatest number (81 species) are prescribed in the treatment of diabetes, 80 species in the treatment of malaria, 56 species in the treatment of diarrhea. The Eremomastax speciosa, Justicia secunda, Annona muricata, Zingiber officinale, Kalanchoe coccinea, Vernonia amygdalina and Ageratum conyzoïdes species had 100% fidelity indices in ...
Chloroquine (diphosphate) is an antimalarial and anti-inflammatory drug widely used to treat malaria and rheumatoid arthritis. Chloroquine is an inhibitor of autophagy and toll-like receptors (TLRs). ...
Already, scientists are using CRISPR to breed mosquitos that cannot transmit malaria, an application that would save thousands of lives. Others are working to create a stronger rice plant that can withstand floods and drought caused by climate change. ...
The principal programme to date is the Millennium Development Goals of which one of the goals is to combat HIV/Aids, Malaria and other diseases since 26 million Sub-Saharan citizens have HIV. ...
The WHO report presents the latest data and in-depth analysis for the key areas outlined in the health SDGs: reproductive, maternal, newborn, child and adolescent health; infectious diseases including HIV, tuberculosis, malaria, hepatitis and neglected tropical diseases; noncommunicable diseases (NCDs) including heart disease, cancer and diabetes; mental health and ...
Prof Hunter and his co-authors list reported fears of the spread of West Nile fever, leishmaniasis, Rift Valley fever, malaria, tick-borne encephalitis and other fearful infections as possible threats to Europe. There were even warnings 25 years ago that climate change could make malaria − another mosquito-borne disease − once again a European ...
When we think of major health threats to people in Africa we often recall HIV/ Aids, Malaria or other preventable diseases such as Polio or Measles, yet there is a threat present in almost every home which takes more life than these well know conditions, almost no one outside Africa is aware of it and It lives in the heart of every ...
The focus in this paper is to assess whether the increase in (global) temperature would result in increase in malaria transmission in Burundi. The analysis carried out in this work exploits real data collected in Burundi, namely monthly rainfall, temperature and humidity data as well as monthly malaria morbidity data for the period 1996-2007. We propose a ...