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Patient Survival Articles & Analysis

35 articles found

Using artificial intelligencepowered evidence-based molecular decision-making for improved outcomes in ovarian cancer

Using artificial intelligencepowered evidence-based molecular decision-making for improved outcomes in ovarian cancer

There is a pressing need for alternative precision medicine solutions to better characterize patients for individualized treatment decisions. If clinicians could better define the prognosis for these patients, their clinical management, monitoring, and systemic treatment decisions could be optimized to improve survival outcomes. To address this ...

ByPredictive Oncology Inc.


Unveiling the Role of CD73: A Key Player in Immune Regulation and Beyon

Unveiling the Role of CD73: A Key Player in Immune Regulation and Beyon

Additionally, adenosine binds to the A2B receptor expressed by cancer cells themselves, facilitating tumor cell survival and proliferation. Further complexity arises as cancer cells also express the adenosine A1 receptor (ADORA1) and A3 receptor (ADORA3). ...

ByBeta Lifescience


Who Needs CPR Training? 11 Careers That Benefit From It

Who Needs CPR Training? 11 Careers That Benefit From It

Having CPR skills enables these professionals to give immediate care until medical professionals come. This helps improve survival rates in emergencies. Flight Attendants and Cabin Crew Flight attendants are responsible for the safety and well-being of passengers on board. ...

ByRescue Solutions LLC


Analytical Approaches and Applications of Whole Exome Sequencing (WES) in Oncology

Analytical Approaches and Applications of Whole Exome Sequencing (WES) in Oncology

Identifying HRD becomes crucial in guiding drug therapy and monitoring patient prognosis. In one study, WES analysis of 9321 patients with colorectal cancer (CRC) revealed that 13.6% of cases were HRD positive, demonstrating higher incidence in MSI tumors compared to MSS tumors. The study also found that overall survival was longer in ...

ByCD Genomics


The Tumor Marker: Vascular Endothelial Growth Factor 165 (VEGF165)

The Tumor Marker: Vascular Endothelial Growth Factor 165 (VEGF165)

The Value of VEGF in Tumor Screening Most tumor patients are diagnosed in the middle to late stages, and early screening and timely diagnosis of suspicious or asymptomatic patients can improve the survival rate of tumor patients and prolong their overall survival. ...

ByBeta Lifescience


ADC Drugs For HER2 Positive Breast Cancer

ADC Drugs For HER2 Positive Breast Cancer

Although more drug choices such as pertuzumab and lapatinib on the basis of trastuzumab significantly prolong the survival of patients and further improve the prognosis, many patients are not sensitive to treatment and relapse and drug resistance occur in a short time, and the efficacy of traditional HER2-targeted drugs for breast cancer ...

ByHunan Huateng Pharmaceutical Co. Ltd.


ADC Drugs For Breast Cancer Treatment

ADC Drugs For Breast Cancer Treatment

The development and marketing of new drugs have far-reaching significance in improving the survival of breast cancer patients and changing the pattern of breast cancer treatment. ...

ByBiopharma PEG Scientific Inc


PEG Linkers for Antibody Drug Conjugates

PEG Linkers for Antibody Drug Conjugates

However, through a large number of clinical studies, it was found that it could not improve the survival rate of patients, and had extremely serious side effects, so it was withdrawn from the market in 2010. ...

ByBiopharma PEG Scientific Inc


Adenocarcinomas and Their Often Misleading Symptoms When Dyspepsia Is an Indication of Cancer - Case Study

Adenocarcinomas and Their Often Misleading Symptoms When Dyspepsia Is an Indication of Cancer - Case Study

Medical History Jane is a 40-year-old, married mother of two teenage boys. She teaches at the local elementary school and has been in good health for most of her life. She has no surgical history. Her most severe ailment up to this point has been the flu at age 27. Her students are first-graders; they are often difficult to control. She also experiences the normal stresses of raising ...

ByThe Medical Algorithms Company Limited


FDA Approved ALK Inhibitors for ALK-Positive Non-Small Cell Lung Cancer

FDA Approved ALK Inhibitors for ALK-Positive Non-Small Cell Lung Cancer

In recent years, the application of targeted therapies has significantly prolonged the survival of patients. However, drug resistance, brain metastases, and other problems have become increasingly prominent in clinical practice. ...

ByBOC Sciences


Comparison of genomic signatures of non-small cell lung cancer recurrence between two microarray platforms

Comparison of genomic signatures of non-small cell lung cancer recurrence between two microarray platforms

Materials and Methods We analyzed gene expression in frozen lung cancer tissue from 59 selected patients who had undergone surgical resection of NSCLC. These patients were divided into two groups: group R, patients who had a tumor recurrence within four years, n=37; group NR, patients who remained disease-free four years ...

ByAuspex Diagnostics


A new model using artificial intelligence to predict recurrence after surgical resection of stage I-II non-small cell lung cancer.

A new model using artificial intelligence to predict recurrence after surgical resection of stage I-II non-small cell lung cancer.

We excluded patients who had follow up time less than 3 years or received adjuvant therapy and had not had a recurrence, as well as patients with missing specimen blocks. ...

ByAuspex Diagnostics


Novel Mechanism of Glycosylation Regulating Pancreatic Cancer Reveled

Novel Mechanism of Glycosylation Regulating Pancreatic Cancer Reveled

Pancreatic cancer is a highly malignant digestive system tumor, and the five-year survival rate of patients after diagnosis is only about 10%. Changes in metabolism are one of the important features of tumor cells. ...

ByCD BioGlyco.


Methylation Markers of Pancreatic Cancer categorization and prognosis evaluation

Methylation Markers of Pancreatic Cancer categorization and prognosis evaluation

Background Pancreatic cancer is one of the highest mortality rate cancers worldwide with 5-year relative survival of 10.8%. Lack of screening methods for early-stage detection as well as proper patient sub-characterization, make it a fatal cancer due to poor diagnoses and insufficient treatment. ...

ByUniversal Diagnostics SL


A Combination of Ramucirumab Plus Pembrolizumab Lengthened Survival For Some Lung Cancer Patients

A Combination of Ramucirumab Plus Pembrolizumab Lengthened Survival For Some Lung Cancer Patients

The hazard ratio (80% confidence interval) for overall survival (OS) time for patients in the study group versus those in the standard-of-care group was 0.69 (0.51-0.92). ...

ByHunan Huateng Pharmaceutical Co. Ltd.


A Novel Potential Target for CAR-T Cell Therapy in Human Solid Tumors Discovered

A Novel Potential Target for CAR-T Cell Therapy in Human Solid Tumors Discovered

At present, chimeric antigen receptor T cell therapy (CAR-T) has made significant achievements in the treatment of specific hematological cancers, allowing patients with relapsed/refractory disease to survive longer and become healthier, but in clinical studies, cell therapy has actually not been successful in the treatment of patients with solid ...

ByCreative BioMart


Oncology - Complex Clinical Trials in The Fastest Growing Therapeutic Area

Oncology - Complex Clinical Trials in The Fastest Growing Therapeutic Area

There’s been a huge emphasis on developing new treatments to improve survival in patients with cancer, but these trials have become a costly undertaking for sponsor companies. ...

BySeascape Clinical


The 3rd AIDS patient is "cured"! Has mankind finally conquered AIDS?   

The 3rd AIDS patient is "cured"! Has mankind finally conquered AIDS?  

The key to this patient's recovery was a blood stem cell transplant: The researchers first used chemotherapy drugs to kill the patient's own immune cells and then transplanted new cells that would not be infected by HIV. ...

ByCreative Biolabs


A "miracle" fruit that can enhance the immune response to tumors   

A "miracle" fruit that can enhance the immune response to tumors  

The advent of immune checkpoint inhibitors (ICI) has improved the overall survival of patients with a variety of malignancies. However, the problem of drug resistance to ICI therapy remains a major obstacle limiting its clinical application. ...

ByCreative Biolabs


Cost-Effectiveness of Percutaneous Deep Vein Arterialization for Patients with No-Option Chronic Limb-Threatening Ischemia: an Exploratory Analysis Based on the PROMISE I Study

Cost-Effectiveness of Percutaneous Deep Vein Arterialization for Patients with No-Option Chronic Limb-Threatening Ischemia: an Exploratory Analysis Based on the PROMISE I Study

The reason for this dynamic is as follows: with the increasing clinical effectiveness of the pDVA strategy, improved survival leads to greater healthcare resource utilization among pDVA patients—resulting in costs that patients in the status quo cohort would not incur because of their earlier death. In the base case, the same dynamic can ...

ByLimFlow, Inc.

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