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Tumor Localization Articles & Analysis
6 articles found
For instance, PEGylated liposomes and nanoparticles can be engineered to carry anticancer drugs directly to tumor sites. The EPR (enhanced permeability and retention) effect allows these PEGylated carriers to accumulate in tumor tissues, increasing the local concentration of the drug and reducing systemic side effects. ...
Antibody-drug conjugate (ADC) is one of the fastest growing fields in tumor therapy, which consists of monoclonal antibody (Antibody), linker (Linker) and active drug (Payload). ...
Summary Inflammation is a hallmark of the tumor microenvironment and an area of active investigation. To better understand how tumor inflammation differs from general inflammation, such as in gum disease, Drs. ...
Chimeric antigen receptor T cells (CAR-T) and T cell antigen receptor chimeric T cells (TCR-T) are currently the "top stream" in adoptive T cell tumor immunotherapy. In particular, CAR-T therapy, which has been approved by the FDA, is rewriting the treatment paradigm of some hematological tumors. However, adoptive T cell therapy remains of little success in ...
Interventional Oncology, the 4th pillar of modern cancer care Until the late 90s, modern cancer care consisted of three pillars of treatment: surgery (through tumor resection), radiation therapy, and chemotherapy. These pillars address tumors directly, removing or destroying lesions. ...
CURRENT STANDARD OF CARE The current initial standard of care for aggressive brain tumors—either primary brain tumors (ie, tumors that originate inside the brain) or metastatic tumors (ie, tumors from cancers that originate outside of the brain)—is maximum safe surgical resection. ...