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Clinical Parameter Articles & Analysis
9 articles found
The accurate and timely diagnosis of preeclampsia is critical in management of affected pregnancies to reduce maternal and fetal/neonatal morbidity and mortality, yet difficulties remain in establishing the rigorous diagnosis of preeclampsia based on clinical parameters alone. Biomarkers that detect biochemical disease have been proposed as complements or ...
Methods: Anti-modified albumin autoantibodies, predominantly ACA, were quantitated using a rapid point-of-care test and the data analyzed by ACA and CCP status for correlations with clinical and laboratory parameters and medication. Results: In two cohorts of RA patients (n=168), 55% were positive for anti-modified albumin autoantibodies (here referred to as ...
Symptoms and signs of HF are either too nonspecific or too infrequent, which makes the clinical diagnosis of HF challenging with [14] Imaging Echocardiography remains the main evaluation for HFpEF and provides essential information to estimate elevated LV filling pressure. ...
Other types of ADC Despite its efficacy, most ADCs targeting solid tumors have not progressed beyond phase 2 clinical trials, suggesting that other parameters need to be optimized in order to reach the market. ...
In line with applicable recommendations for U.S. cost-effectiveness analyses, costs and health outcomes were discounted by 3% per year.15,16 We evaluated cost-effectiveness considering willingness-to-pay thresholds of $50,000 per QALY gained (“high-value” intervention per ACC/AHA statement on cost-effectiveness) and $150,000 per QALY gained (“intermediate value” per ...
Do you have a patient with Systemic Lupus Erythematosus (SLE) that you suspect may also have Sjögren’s Syndrome (SS)? With shared clinical and serological features, overlapping SS with SLE is a comorbidity that is often challenging to identify to promptly assist clinical management. ...
However, zone III contained a higher proportion of individuals with chronic diseases, such as hypertension, diabetes, and metabolic syndrome than did zone I. Moreover, many clinical parameters showed significant increases in zone III, including hsCRP (Bonferroni post hoc one-way ANOVA test; p < 0.0001) (Figure 1C), body mass index (BMI), blood pressure, ...
Thisinvestigation is required to establish the mechanical and overall performance specifications ofthe system and to establish baseline parameters for future clinical usage. The applied methods include measurements of energy, focal spot size, beam performance,dosimetry, beam data, treatment planning system, leakage radiation, acceptance testing, ...
Perfluoroalkyl compounds (PFCs) are ubiquitous, persistent chemical contaminants found in the environment, wildlife, and humans. Despite the widespread occurrence of PFCs, little is known about the impact these contaminants have on the health of wildlife populations. We investigated the relationship between PFCs (including Σperfluorocarboxylates, Σperfluoroalkyl sulfonates, perfluorooctane ...