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Diabetes Type Articles & Analysis
64 articles found
If you ignore the snoring and sleep apnea, it can lead to multiple health issues such as hypertension, cardiovascular issues and even Type 2 diabetes. Usually, the gold standard in sleep apnea treatment is CPAP therapy or Continuous Positive Airway Pressure therapy, which helps eliminate the pauses in breathing, as it provides a steady stream of air to your ...
A New Drug to Reduce Heart Attacks and Strokes The newly approved drug Sotagliflozin (Inpefa) has shown promise in reducing heart attacks and strokes among patients with type 2 diabetes and chronic kidney disease. It works as a dual SGLT1 and SGLT2 inhibitor, helping to regulate blood sugar levels while also protecting the heart. ...
This function is particularly important in the context of metabolic disorders such as obesity and type 2 diabetes. Impaired endothelial function in muscle microvasculature can lead to reduced insulin sensitivity and glucose uptake, further exacerbating metabolic dysregulation. ...
MMPs are usually classified into collagenases, gelatinases, stromelysins, matrilysins, membrane-type (MT)-MMPs, and other MMPs based on their substrates and the organization of their structural domains. ...
Diabetes is a common clinical disease, and with the improvement of living standards, an increase in the number of obese people, and the intensification of aging populations, the incidence of diabetes is increasing year by year. Diabetes has various types and requires long-term treatment. Antidiabetic drugs are essential for ...
Assessment of C-peptide levels can identify individuals at risk for or with type 1 diabetes with residual β-cell function in whom β cell-sparing interventions can be evaluated, and can aid in distinguishing type 2 diabetes from Latent Autoimmune Diabetes in Adults and late-onset type 1 ...
Abstract Background: Assessment of short-term glycemic control can facilitate monitoring of diabetes development in at-risk individuals and monitoring response to lifestyle modification or medication. We evaluated salivary protein glycosylation levels as a novel, noninvasive, short-term glycemic index in comparison to hemoglobin A1c (HbA1c), fructosamine, 1,5-anhydroglucitol ...
Dysbiosis, an imbalance in gut microbial communities, has been linked to altered bile acid metabolism and, consequently, to diseases like non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes. A landmark study conducted in collaboration with Creative Proteomics investigated the bidirectional relationship between bile acids and the gut microbiota in ...
Diabetes, specifically Type 1 and Type 2 Diabetes Mellitus, remains one of the most commonly encountered metabolic diseases worldwide. The complexity and diversity of these conditions necessitate the development of detailed medical models for a comprehensive understanding of the diseases. Over time, Type 1 and ...
The most common forms of diabetes are type 1 diabetes and type 2 diabetes. Type 1 diabetes (once known as insulin-dependent diabetes or juvenile onset diabetes) is characterized by insufficient insulin production and the need for daily insulin ...
The effect of low-dose IL-2 and Treg adoptive cell therapy in patients with type 1 diabetes[J]. JCI insight, 2021, 6(18). [5] Whangbo J S, et al. ...
FGL2 and disease Studies have found that FGL2 is highly expressed in microvascular endothelial cells, causing microcirculatory disturbance, promoting myocardial and liver ischemia-reperfusion injury, arthritis, type 2 diabetic heart failure, and type 2 diabetic nephropathy; FGL2 is highly expressed in inflammatory bowel disease ...
Produced using bioreactors, biopharmaceuticals include vaccines, therapeutic proteins, blood and blood components, and tissues.4 Due to their absence of chemicals, biopharmaceuticals have seen a surge in demand and acceptance in recent years.4Could Bioreactors Provide a Cure for Diabetes?Diabetes is a disease caused by the pancreas not producing enough insulin, ...
Metformin is a classic first-line hypoglycemic agent for patients with type 2 diabetes, and is an essential drug in combination regimenes. However, as the evidence is updated, the idea of drug selection for first-line treatment is changing. ...
In addition, our previous study also found that tetrahydrocurcumin has a good therapeutic effect on metabolic syndrome, obesity type 2 diabetes, hypertension, insulin resistance syndrome and other related diseases, and has a wide range of application prospects. 1.Hypoglycemic Effect Murugan P et al. induced type 2 diabetes mouse ...
HFpEF patients are likely to have a high prevalence of cardiovascular and non-cardiovascular comorbidities, such as obesity, metabolic syndrome, diabetes mellitus type 2, salt-sensitive hypertension, atrial fibrillation (AF), chronic obstructive pulmonary disease, anaemia, and renal dysfunction.[6.7,8] As life expectancy and comorbidity rates rise, the ...
The aim of this project is to develop low dose IL-2 for treatment of early onset juvenile Type I diabetes. Low dose injectable IL-2 in animal models has been shown to restore the balance between regulatory and effector T cells and, in this way, can help to reverse autoimmunity and the development of type I diabetes. Looking ...
Liraglutide and exenatide are both belonging to the class of diabetes products called GLP-1 analogues. The GLP-1 analogues have established themselves in the past years as one of the superior drug classes for treatment of diabetes type II in terms of blood glucose lowering and weight loss. ...
BioLingus will position these products in the “epidemic” markets of obesity and type II diabetes : More than 400 MM people suffer from diabetes today. The global type 2 diabetes market is expected to grow to $58.7 billion by 2025, with an annual growth rate of 6.5%, according to research and ...
Our sublingual “insulin+” product will be positioned in a particular segment of this market : it will be prescribed for type II diabetes patients, who do not respond sufficiently to GLP-1 analogues alone. ...