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Liver Cell Articles & Analysis
28 articles found
While spherical nanoparticles are easily encapsulated and engulfed by cell membranes, the contact angle and curvature of disc-shaped particles make it difficult for macrophages to "eat" them. ...
Non-alcoholic fatty liver disease (NAFLD) has emerged as a significant public health concern, associated with obesity, insulin resistance, and a spectrum of metabolic disorders. ...
Hepatocytes are the chief functional cells of the liver, responsible for the selective uptake, metabolism and excretion of most drugs. ...
It has good biofilm property and containment and can promote cell uptake and endosomal escape while avoiding nuclease degradation. The positive charge carried by cationic liposomes can neutralize the negative charge carried by siRNA to form a tightly structured complex that greatly extends the cycle time and facilitates the delivery of siRNA. Peptide-siRNA Conjugates ...
Subsequently, apolipoprotein E (ApoE) binds with the LNP to form a corona, which is recognized by low-density lipoprotein receptors on liver cells and promotes LNP internalization. Many studies have followed the prescription of Onpattro to prepare liver-targeted LNPs. ...
Mesenchymal stem cells are multi-potent stromal cells capable of differentiating into various cell types like osteoblasts (bone cells), chondrocytes (cartilage cells), and adipocytes (fat cells). They were initially identified in the bone marrow, but have since been found in various other tissues ...
Pluripotent stem cells — cells with the ability to differentiate into nearly any cell type in the body, constituting a significant potential for regenerative medicine. Among these, induced Pluripotent Stem Cells (iPSCs), in particular, have garnered substantial interest from the scientific community due to their ability to ...
Introduction - MMP-3 MMP-3, also known as stromelysin-1, is a key member of the MMP family. It is synthesized in cells as a proenzyme form (pro-MMP-3) and consists of 477 amino acids. ...
The results showed that tetrahydrocurcumin could significantly reduce the blood glucose of diabetic rats and improve the plasma insulin level, indicating that tetrahydrocurcumin has a good hypoglycemic effect on type 2 diabetes. 2.Anti-oxidative Stress Effect Murugan P et al. used niacinamide to induce diabetic rats, and the results showed that tetrahydrocurcumin could significantly improve the ...
By comparing the toxicity of chitosan oligosaccharides with different molecular weights and different degrees of deacetylation to prostate cancer cells PC3, lung cancer cells A549 and liver cancer cells HepG2, the researchers found that chitosan with low molecular weight and low degree of deacetylation has Better anti-tumor ...
The permeability of the microcirculation, in turn, is determined by properties of a small pore glycocalyx matrix, membrane-bound water transport channels (aquaporin), large diameter intercellular clefts between endothelial cells (sinusoidal cells in the liver and spleen), and a large pore plasma protein transport system. ...
Catalase is an antioxidant enzyme commonly found in almost all living organisms, mainly in chloroplasts, mitochondria, endoplasmic reticulum of plants, liver and red blood cells of animals. It is the marker enzyme of the peroxisome, accounting for about 40% of the total peroxisomal enzymes. ...
For example, the definitive erythroid cells appeared predominantly in the liver. Intermediate mesoderm was identified in the internal organ region, and radial glia were mainly distributed in the CNS. ...
Loss of glutathione reductase makes cells more sensitive to oxidants and antibiotics. For patients with liver damage, the detection of glutathione reductase can enable us to understand whether the function of the body's glutathione antioxidant system is sound. The reduction of glutathione reductase indicates that the detoxification function and antioxidant ...
When liver regeneration is severely impaired in mice, BECs can develop into hepatocytes or bile duct cells. This bipotential cell population can be isolated, expanded, and transplanted to repopulate the damaged liver soft tissue and differentiate into mature hepatocytes in order to restore liver function when ...
Alcohol dehydrogenase is abundant in human and animal liver, plant and microbial cells. It is a zinc-containing metalloenzyme with broad substrate specificity. ...
Graphical Abstract Keywords microbiome alcohol liver diseases roseburia fat liver diseases hepatitis occludin liver steatosis leaky gut Introduction Long-term excessive alcohol consumption is the most important risk factor for the development of alcohol-related liver diseases (ALDs), including alcoholic ...
Many may not have heard of nonalcoholic fatty liver (NAFL) yet it is a very common condition. If NAFL is not addressed, it can progress to a serious condition known as Nonalcoholic fatty liver disease (NAFLD) Non-alcoholic fatty liver is the buildup of extra fat in liver cells that is not caused by alcohol. It is ...
ByAlgatech
Studies shows that silymarin may help with the regeneration of liver cells, decrease inflammation and protect liver cells from damage in an antioxidant type mannerriiil « Read: Study shows FucoVital to be more effective than silvmarin in preventing harmful fat accumulation in liver cells ...
ByAlgatech
NAFLD is now recognized as the most common cause of chronic liver disease in the western world, with an estimated prevalence of 25% worldwide, and is projected to become the leading indication for liver transplant by 2025. ...