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Metabolic System Articles & Analysis
16 articles found
Plant cell viability refers to the proportion of living, metabolically active cells in a given sample. It provides insight into cellular health, growth potential, and the effects of treatments such as cryopreservation, toxins, or genetic modification. ...
S9 metabolic stability assays provide critical insights into how a compound behaves within biological systems, especially concerning its metabolism, stability, and overall pharmacokinetics. ...
One essential approach to studying cellular metabolism is Metabolic Flux Analysis (MFA), a powerful tool that reveals the intracellular activities and metabolic dynamics of living systems. ...
Genetic models, such as those developed in mice with specific mutations related to lipid metabolism or obesity, provide insights into the genetic predispositions that underlie NAFLD. ...
Hepatocytes are the chief functional cells of the liver, responsible for the selective uptake, metabolism and excretion of most drugs. Cells for use in plate cultures or suspension assays represent a key tool for predicting properties such as hepatotoxicity, metabolism, and potential drug-drug interactions. ...
The prevalence of AF in HFpEF ranges from 15% to 40%,[26,27,28,29] and it seems to implicate a worse prognosis in patients with HFpEF than HFrEF.[30] If both heart failure and AF coexist, the risk for worse outcomes and hospitalizations increases significantly, with a two-fold increase in mortality.[31] AF and HFpEF appear to both be manifestations of a common underlying atrial and ventricular ...
Researches focus on disease-related genes, regulatory and interaction systems, metabolic systems, genetic variation, laboratory diagnosis and specific prevention, drug resistance genes, virulence genes and so on. Specifically, microbial whole genome sequencing can be applied to: · Diagnosis and identification of pathogens · ...
The beneficial effects of hyperoxia supplementation on oxygen transport system capacity, lactic acid metabolism capacity, power output performance, and endurance exercise tolerance have been described in multiple previous studies (Sperlich et al., 2017; Cardinale and Ekblom, 2018). ...
It revealed a novel mechanism by which the deubiquitinosomal system senses metabolic signals such as glucose and fatty acids and regulates energy metabolism. ...
Although the influence of exercise on energy metabolism is well recognized, there is still a lack of study on how exercise timing affects metabolic state, and we are still unaware of the similarities and differences between different exercise time periods. This question is answered in a recent publication published in Cell Metabolism. ...
In addition to various delivery systems, the use of excipients helps to bring peptides into drug development. ...
The gut microbiota, which includes Akkermansia muciniphila, is known to modulate energy metabolism, glucose tolerance, immune system maturation and function in humans1,2,3,4. Although A. muciniphila is correlated with metabolic diseases and its beneficial causal effects were reported on host metabolism5,6,7,8, the molecular mechanisms involved ...
Liver protection: Hydrogen can remove the malignant free radicals produced by ethanol during metabolism, promote metabolism and protect the liver. Sub-health: Hydrogen can penetrate deep into the tissue or cell membrane space, activate cell tissue, improve the state of stress, and is a younger body. Malignant tumor: It can prevent the infinite division ...
Abstract Electronic nicotine delivery systems (ENDS) or e-cigarettes have emerged as a popular recreational tool among adolescents and adults. ...
CB1 is mainly found on cells in the nervous system, including certain areas of the brain and the ends of nerves throughout the body, while CB2 receptors are mainly found in cells from the immune system. ...
The ratio of Receptor Activator of Nuclear Factor κB Ligand (RANKL) and Osteoprotegerin (OPG) has become an important marker to assess the status of systemic bone metabolism and has been shown to be dysregulated in AS patients. ...