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Patient Sample Articles & Analysis
41 articles found
The ACE program supports academic researchers in their early drug discovery and development initiatives by providing access to the POAI proprietary active machine learning platform and frozen patient DTC samples. Through this project, the POAI active machine learning technology constructed a predictive model of tumor sample response to ...
Latex Agglutination Assays: The Role of Dyed Polystyrene Particles Latex agglutination is the change in agglutination capacity observed when a sample containing a specific antigen is mixed with antibodies coated on the surface of latex particles. Agglutination can also be reversed by coating latex particles with specific antigens and testing the sample for the ...
Targeted drug screening involves the examination of candidate drugs in the context of resistant cell lines or patient-derived samples, providing a more accurate representation of how therapies will perform in actual patient scenarios. ...
These beads can simultaneously capture multiple target analytes from one sample — such as cytokines or growth factors — while a detection system measures the interaction through fluorescence readouts. ...
An emerging approach for translational cancer research is patient-derived xenografts in zebrafish embryos (zPDX). Tumor cells from primary or metastatic human cancers collected by surgery or biopsy procedures were transplanted into zebrafish. ...
To test for fructose intolerance, the patient would need to ingest 25g of fructose in 250ml of water. Breath samples would then be taken at 30-minute intervals over 3 hours. ...
Although frontline treatment of chemotherapy and surgery is often effective, with nearly all patients experiencing remission, over 80% of patients will experience disease recurrence in the first two years and ultimately die of the disease. Only 20% of patients with ovarian HGSC will be long-term survivors, but no current clinical data can ...
There were several software packages available on the market, but none which provided a complete solution to manage samples, the sample source (in Dr Lindsay’s case – the patient) and the storage area. ...
These innovative approaches include genetic testing, next-generation sequencing, and biomarker analysis, which allows for more accurate and early detection of rare diseases by analyzing a patient's genetic makeup or identifying specific biomarkers in their blood or tissues. ...
Kits are shipped directly to users and completed samples are shipped back, so participation is possible without ever leaving home. Using Tasso would produce the patient-centric sampling experience and high quality blood sample that the Theberge Lab needed. ...
By analyzing gene expression patterns in patient samples, scRNA-seq can identify molecular signatures associated with drug response or disease progression. ...
To explore this further, researchers collected samples from 346 IBS patients and 170 healthy control (HC) individuals, who completed dietary inventory surveys to reflect their most frequently consumed diets. Subsequently, fecal samples were collected from 171 IBS patients and 98 HC individuals for 16S rRNA gene sequencing and ...
Traditional models often fail to capture the cellular heterogeneity observed in human tissues, limiting their predictive value for drug responses. Profiling patient samples using scRNA-seq helps identify cell types relevant to the disease and develop more accurate disease models. ...
Enzyme-based diagnostic tests are typically performed by measuring the activity of specific enzymes in a patient's blood or other bodily fluids. These tests are highly sensitive and can detect even small amounts of enzymes, which can be indicative of a disease or condition. ...
These statistics demonstrate the need to address a patient’s specific genetic make-up and phenotype by adopting a personalized treatment methodology for cardiovascular diseases. ...
It can label up to 8 samples at once depends on the iTRAQ kit, which contains reporter group, peptide reactive group and balance group. ...
Adjuvant treatment benefits stage II and III patients, but not stage I patients, and most studies fail to predict recurrence in stage I patients. ...
The coating is dry and no mixing of additional fluids is required. After a patient coughs into the tube, the technician closes the plunger and rotates the upper half of the tube, thereby engaging the tube’s dynamics to create a disc of cough sample and position it over the biosensor. ...
We hope those become medicines that are valuable to patients and create revenue for us, but ultimately, the real value is in improving our platform. ...
A 2020 study confirmed B. quintana DNA in 19.3% of dental samples collected from nine archeological sites that spanned 1900 years. ...