Activated Sludge Metabolic Articles & Analysis: Older
31 articles found
Anorexia, a condition characterized by a significant reduction in food intake despite negative energy balance, poses severe risks to health and quality of life. It manifests in various forms in humans, including anorexia nervosa and physiological anorexia. While psychological and social factors have been widely studied, the physiological causes remain less understood. For ground squirrels, ...
Optical Rotatory Dispersion (ORD) and Circular Dichroism (CD) are two important techniques widely used in the study of biomolecules, particularly the structure of proteins and nucleic acids. These techniques are based on the interaction of molecules with light, specifically how the molecules affect plane-polarized light that passes through them.Optical Rotatory Dispersion1. FundamentalsORD is ...
Bedfont® Scientific Limited hosted an insightful webinar Mastering Gut Health: Understanding SIBO, Carbohydrate Malabsorption, and Accurate Gastrointestinal Investigation. Gastrointestinal Physiologist and Bedfont® Medical Advisory Board member Melissa Dooley, led the discussion and shared valuable information on various gastrointestinal disorders and the importance of not ...
Circular Dichroism (CD) uses the absorption properties of optically active substances to analyze the molecular structure of drugs. It has very valuable applications in drug analysis, including:1. Identification of Drug StereochemistryMany drug molecules are chiral, and their activity, metabolism, and toxicity can significantly differ due to stereochemistry. CD can differentiate the different ...
Introduction Cellular mechanisms driving cell death play a crucial role in various physiological and pathological processes. One such mechanism is apoptosis, a tightly regulated process vital for maintaining tissue homeostasis, development, and immune response. Apoptosis assays are valuable tools used by researchers to study the intricate details of this cellular event. This blog aims to ...
Metabolism is the assembly of biochemical reactions in living organisms, the material basis for life maintenance of living organisms, and an important basis for the study of life activities. Metabolomics studies the endogenous metabolic activities of life under the influence of the internal and external environments, including the detection and analysis of metabolite types and quantities and ...
AMPK (Adenosine 5'-monophosphate (AMP)-activated protein kinase), as an important kinase regulating energy homeostasis, is one of the central regulators of eukaryotic cell and organism metabolism. It is responsible for regulating cellular capacity input and output and maintaining the smooth functioning of cellular physiological activities. AMPK is also a key protein involved in various signaling ...
Previously, it was thought that glial cells, which support neuronal activity, metabolize most of the glucose in the brain. However, by using induced pluripotent stem cells, the researchers found that neurons were able to take up glucose and process it into smaller metabolites. In mice, normal function of neurons depends on glycolysis. The findings could help develop new treatments for ...
Microbes are present almost everywhere. They play a vital role in cycling carbon, release important compounds, and may be associated with infectious diseases. Metagenomics is the culture-independent genomic research of microbial communities. Metagenomics presents a powerful tool to study prokaryotes and viruses in the environment via the analysis of their DNA obtained directly from environmental ...
What is metatranscriptomic sequencing? Metatranscriptomic sequencing provides direct access to culturable and non-culturable microbial transcriptome information by large-scale, high-throughput sequencing of transcripts from all microbial communities in specific environmental samples. Metatranscriptomic sequencing offers an opportunity to randomly sequence mRNAs as a unit for understanding the ...
Microbes are present almost everywhere. They play a vital role in cycling carbon, release important compounds, and may be associated with infectious diseases. Metagenomics is the culture-independent genomic research of microbial communities. Metagenomics presents a powerful tool to study prokaryotes and viruses in the environment via the analysis of their DNA obtained directly from environmental ...
The drug developer's latest capital raise, a $150 million private placement, comes during a difficult market environment. The strongest companies can raise money in any environment. Recursion Pharmaceuticals (RXRX) - Get Free Report recently raised $150 million in gross proceeds from a private placement of common stock, including half from a single fund that has never before invested in the ...
Overview of Cytochrome P450 Cytochrome P450 (CYP450), is a family of hemoglobin-coupled monooxygenases. In mammals, CYP450 oxidizes steroids, fatty acids, and xenobiotics, playing an important role in the metabolism of various compounds as well as in the synthesis and breakdown of hormones. In plants, they regulate the synthesis of defense compounds, fatty acids, and hormones. With the progress ...
Gut microbes are considered "virtual organs" that influence host health and are involved in disease research. The human gut microbiota has a large gene pool, encoding approximately 100-150 times more genes than the human genome, and contains a rich resource of enzymes with the ability to metabolize drugs. The diversity of gut bacteria also affects the mental health of the host. Microbiomes from ...
The epigenome is composed of chemical markers and proteins that can attach to DNA and direct the function of gene regulatory elements, controlling the production of proteins in specific cells, among other roles. Common epigenomic modifications include methylation of the nucleotide cytosine and histones or acetylation and phosphorylation of histones. All of these modifications do not change the ...
In a new study, researchers from the Icahn School of Medicine at Mount Sinai have developed a reproducible and scalable method to advance the maturation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs), and hPSC-CMs produced by human stem cell lines in the laboratory support myocardial contraction, which will improve methods for disease modeling, regenerative therapy, and drug ...
Life is all about working out. Moderate exercise not only strengthens the body, but also improves the metabolic state and slows the progression of diseases. However, different times of exercise may have different impacts, and it is an intriguing scientific question how to determine the best time to exercise. Although the influence of exercise on energy metabolism is well recognized, there is ...
What is a hybrid system? Choosing between a traditional lighting system such as High Pressure Sodium (HPS) or Metal Halide (MH) lighting and newer Light Emitting Diode (LED) technology can be a complicated decision. Factors such as energy use, ROI, maintenance costs and how they affect the growth of your plants should be considered. Many growers are looking to switch over to LED lighting ...
Abstract Protease proprotein convertase subtilisin-like kexin type 9 (PCSK9) is an important target for the treatment of hypercholesterolemia. PCSK9 is synthesized as a zymogen that undergoes autocatalytic processing and secretion. Secreted PCSK9 binds to the LDL-receptor (LDLR) and chaperones it to the degradation pathway. Several pharmaceutical companies have developed injectable mAb PCSK9 ...
Abstract Summary Polyetheretherketone (PEEK) is an alternative to metallic implants in orthopedic applications; however, PEEK is bioinert and does not osteointegrate. In this study, an accelerated neutral atom beam technique (ANAB) was employed to improve the bioactivity of PEEK. The aim was to investigate the growth of human mesenchymal stem cells (hMSCs), human osteoblasts (hOB), and skin ...