Allergen Specific Articles & Analysis
3 articles found
Thymic Stromal Lymphopoietin (TSLP) is a multifunctional cytokine that acts on various cell types, including dendritic cells, T cells, B cells, neutrophils, mast cells, eosinophils, and innate lymphoid cells, affecting their maturation, survival, and recruitment. It is well-known for its role in promoting type 2 immune responses, such as allergic diseases. In 2021, a monoclonal antibody targeting ...
Lipopolysaccharide (LPS) can promote or prevent allergic reactions of T helper cells (Th2), but the molecular mechanism behind it is not clear to researchers at present; immunologists have long been confused about LPS, which is a lipopolysaccharide molecule of bacteria, which can help form the cell wall of gram-negative bacteria; many experiments have shown that LPS exposure may protect the body ...
In recent years test systems have been described that may be applied routinely to discriminate between contact allergens and irritants in vitro. Using human monocyte-derived dendritic cells (MoDC), this study was designed to refine the settings of a potential routine screening protocol for contact allergens and to investigate the so far poorly defined concentration dependency of contact ...