Allergen Specific Articles & Analysis
6 articles found
TSLP and Diseases TSLP and allergic reactions The discovery of the association between allergies and the activity of allergen-specific TH2 cells has led to the crucial hypothesis of the role of TSLP in the development and maintenance of atopic allergic diseases. ...
Abstract Background: The sublingual mucosa has been used for many years to apply allergenic extracts for the purpose of specific immunotherapy (IT). Although sublingual IT (SLIT) is both safe and efficacious, the density of antigen-presenting cells is higher in other regions of the oral cavity and vestibule, which make them a potentially desirable target for IT. ...
Cysteine proteases can induce non-classical monocytes in the lungs to produce the cytokine GM-CSF (granulocyte-macrophage colony-stimulating factor) through a mechanism that is not clear, and GM-CSF signaling can control LPS to inhibit Th2 cell responses to allergens, such as house dust mites. Therefore, because the protective effect of LPS depends on GM-CSF, the beneficial ...
Discussion Our study demonstrated that the administration of specific Lactobacillusstrain could significantly alleviate the symptoms of AD via modulation of the immune response and gut microbiota. ...
Those of us involved in the food allergen analytical community are constantly striving to improve allergen detection methods. ...
In recent years test systems have been described that may be applied routinely to discriminate between contact allergens and irritants in vitro. Using human monocyte-derived dendritic cells (MoDC), this study was designed to refine the settings of a potential routine screening protocol for contact allergens and to investigate the so far poorly defined ...