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In today’s highly regulated industrial landscape, ensuring SIL2 compliance in additive manufacturing and pharmaceutical production is critical. These sectors rely on accurate, safe, and compliant equipment to maintain operations and protect both employees and end-users. One standard that has emerged as a benchmark in safety-critical processes is SIL2 compliance. This article explores what ...
In the realm of genetic engineering and genome editing, single guide RNA (sgRNA) plays a pivotal role, particularly in the context of CRISPR-Cas9 technology. The effectiveness of CRISPR-Cas9 hinges largely on the design and confirmation of sgRNAs, which direct the Cas9 protein to specific genomic locations. This article delves into the key aspects of designing sgRNAs, the methodologies involved ...
Introduction Good Manufacturing Practice (GMP) cell banks play a crucial role in the biopharmaceutical industry, serving as foundational repositories of cell lines used for the production of therapeutic biological products. Characterization of these cell banks is essential to ensure the safety, efficacy, and consistency of the biopharmaceuticals derived from them. This article will explore the ...
Nuclear receptors are a class of proteins that play a vital role in cellular communication, gene expression, and overall homeostasis within the body. They act as transcription factors, responding to various stimuli, including hormones, nutrients, and even environmental agents. Due to their crucial roles in physiological and pathological processes, nuclear receptors have emerged as significant ...
Glycosylation site detection refers to identifying the location where glycosylation occurs in biomolecules. Glycosylation is a biochemical modification process that involves linking sugar molecules to other biomolecules (such as proteins, nucleic acids, or lipids), thereby affecting their structure and function. Glycosylation plays a critical role in organisms, but it may also be associated with ...
DIA (Data Independent Acquisition) proteomics sequencing is used for high-throughput, high-sensitivity proteomics analysis. Compared with the traditional DDA (Data Dependent Acquisition) technology, DIA technology can provide a more comprehensive proteome coverage and more reliable quantitative results. DIA technology has a wide range of applications in biomedical research, disease biomarker ...
Creative Biogene is revolutionizing the field of microbial gene expression with its cutting-edge services and expert team of scientists. As a leading company in this area, Creative Biogene offers the best microbial gene expression service to help researchers and scientists achieve their research goals quickly and efficiently. With years of development and research experience, Creative Biogene's ...
Overview Cleanrooms are essential in the pharmaceutical industry, providing controlled environments for the aseptic production of sterile products. Recently, big data analytics has emerged as a transformative tool, offering new ways to enhance cleanroom performance beyond traditional ...
MSCs exhibit specific morphology, which makes them unique compared to other cell types typically used in CLD. While forming spindle-shaped, elongated, and transparent cell projections, the MSCs can pose a significant challenge when it comes to imaging and subsequent image analysis. Many imaging systems on the market are simply not fit for precise detection of these unusual cell types. ...
Flow cytometry (FC) is an important tool for analyzing complex pathways and responses of single cells, which can track cell phenotypes and functions in multiple dimensions. It is also increasingly applied in drug development. FC not only can detect intracellular and extracellular components, but also detect soluble analytes in serum or plasma samples, such as cytokines, drug complexes, or ...
It can be widely used in immunoassay, nucleic acid research, enzymatic analysis, receptor and ligand recognition analysis, and other researches. ...
Finally, CD Genomics provides detailed analysis reports that help researchers gain an in-depth understanding of T-cell clone diversity and clonality in the samples. ...
There is no such thing as unimportant, or non-eloquent, brain. For decades, neuroscientists and clinicians have studied the brain attempting to pinpoint the regions that control specific functions. This is the age old question of ‘What part of the brain is responsible for ___?’ For clinicians, this assists in determining where the source of certain disorders may originate and ...
HLA genotyping bioinformatics solutions are designed to provide reliable, accurate and reproducible results to infer the precise variation in HLAs and to understand the relationship between HLA polymorphisms and the etiopathogenesis of diseases. ...
They are providing a service according to the needs of hospitals, faculties, research centers, and clinical analysis. One of their business units is the marketing of reliable individual and multipanel blood and urine lateral flow tests. ...
ByIUL S.A.
Virasoft provides digital pathology systems that optimize the pathology workflow with digital slide management, slide viewing and quantitative image analysis for Acibadem Hospitals pathology laboratories. In partnership with Acibadem Hospitals and Virasoft, artificial intelligence projects are being developed for several cancer diagnosis. Digital Pathology System ViraCenter is an integrated ...
Two stability research methods If the parameters indicate that stability changes with time, regression analysis is the main method to determine stability, because time is the main factor affecting stability. ...
Healthcare provider organizations (HPOs) are starting to recognize the value of consolidating vendors and implementing an Enterprise Risk Management solution that is both holistic and comprehensive. But finding software – and a vendor – that can fulfill the promise of a true integrated solution for Enterprise Risk Management in healthcare can be tricky. Part of the challenge is ...
In this new era where everything can be connected, customers prefer complete solutions to stand-alone products.In this context, BRAIN by PICVISA was developed; a consultancy, analysis and feasibility studies service aimed at those industries interested in promoting the automation of their plants. ...
The Client Multinational pharmaceutical company - Europe The cooperation on digitally supported services started in 2019 in one of the customer’s manufacturing facilities in Europe. The site of the first contract had multiple water rooms generating purified water with some equipment supplied by Veolia Water ...