Antigen Affinity Articles & Analysis
5 articles found
They have the advantages of small size, high stability, and good penetration, and therefore have a wide range of application prospects in the fields of clinical treatment, diagnostic reagent development, etc.Characteristics of NanobodiesThe size of nanobodies usually ranges between 10-15kDa, which is only 1/10 of the size of regular antibodies. Their unique antigen-binding ...
Smaller volume Nbs can achieve higher tissue penetration and stronger cell killing in vivo.Antigen recognition ability: Among all complementarity determining regions, CDR3 accounts for 60-80% of the antigen recognition specificity. The CDR3 loop is long and extended. This characteristic gives VHH better antigen recognition specificity and ...
Antibody Backbone: The Starting Point for ADC Design l Selection of antigen specificity Since the mechanism of ADCs begins with the binding of target cells, the antibody should have high specificity for the target antigen. ...
FGF acidity was detected in submerged-fixed paraffin-embedded sections of the human mammary gland using goat anti-human FGF acidic antigen affinity-purified polyclonal antibody at 15 µg/mL overnight at 4 °C. ...
Here, using a genetic timestamping system in mice, we show that persistent PCs accrue in bone marrow at an approximately constant rate of one cell per hour over a period spanning several weeks after a single immunization with a model antigen. Affinity-based selection was evident in persisting PCs, reflecting a relative and dynamic rather than absolute ...