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Biomarker Discovery Articles & Analysis

17 articles found

An Introduction to Metabolic Flux Analysis and Metabolomics Services

An Introduction to Metabolic Flux Analysis and Metabolomics Services

Disease Research: By mapping altered flux patterns in cancer cells, cardiovascular diseases, or diabetes, MFA helps identify potential metabolic vulnerabilities or biomarkers for diagnosis and therapy. Agricultural Sciences: MFA can uncover mechanisms by which plants adapt to environmental stresses, aiding in crop improvement. ...

ByCreative Proteomics


Unveiling the Role of Nicotinamide Adenine Dinucleotide (NAD): A Key Player in Cellular Metabolism and Disease Research   

Unveiling the Role of Nicotinamide Adenine Dinucleotide (NAD): A Key Player in Cellular Metabolism and Disease Research  

Understanding and analyzing these biomolecules has become increasingly important in areas such as disease research, biomarker discovery, and drug development. NAD and NADH are not merely passive participants in metabolism—they are regulatory molecules that influence key metabolic pathways, including glycolysis, oxidative phosphorylation, and biosynthetic ...

ByCreative Proteomics


HCEC-12 Cell Line: An Overview of Its Characteristics and Applications

HCEC-12 Cell Line: An Overview of Its Characteristics and Applications

Gene Expression Studies: HCEC-12 allows for the examination of gene expression profiles in response to different stimuli, paving the way for biomarker discovery and understanding the genetic basis of corneal diseases. ...

ByCreative Bioarray


Ribonuclease: A Cornerstone of RNA Biology

Ribonuclease: A Cornerstone of RNA Biology

Furthermore, the application of RNases in biomarker discovery offers promising avenues for diagnosing and treating a variety of conditions, offering insights into cellular responses under stress or disease pathways. ...

ByCreative Enzymes


Single Clone Antibody Variable Region Sequencing

Single Clone Antibody Variable Region Sequencing

Monoclonal antibodies are highly specific biological molecules that are crucial in many areas like disease diagnosis, treatment, and biomarker discovery. They can trigger an immune response in the human body by recognizing and binding to specific antigens, thereby combating pathogens. ...

ByMtoZ Biolabs


Alfa Cytology Announces Pancreatic Cancer Vaccine Development Services to Explore Reliable Immunotherapy in Preclinical Trails

Alfa Cytology Announces Pancreatic Cancer Vaccine Development Services to Explore Reliable Immunotherapy in Preclinical Trails

About Alfa Cytology Alfa Cytology is a biotech company focused on providing early discovery and development of preclinical studies. The team works closely and communicates actively to achieve their common goals of helping researchers and professionals understand PC biology, explore new PC therapeutics & protocols, and develop new PC biomarkers. ...

ByAlfa Cytology


Q&A: The evolving role of antibody-drug conjugates in oncology

Q&A: The evolving role of antibody-drug conjugates in oncology

Dr. Kate Sasser from Tempus led a discussion on the potential of antibody-drug conjugates (ADCs), their challenges in targeting tumor antigens, and the future of cancer treatment with Dr. Daniel Johnson, Dr. Funda Meric-Bernstam, and Dr. Kellogg Parsons. The oncology field is rapidly advancing with the development of antibody-drug conjugates (ADCs), offering new hope for ...

ByTempus


Dia Protein Group Sequencing

Dia Protein Group Sequencing

DIA technology has a wide range of applications in biomedical research, disease biomarker discovery, and drug development.DIA Proteomics SequencingDIA technology systematically scans the entire mass range during mass spectrometry analysis, rather than analyzing only a few preselected ions. ...

ByMtoZ Biolabs


Small Molecule Drug Development at Alfa Cytology: Transforming Cancer Research

Small Molecule Drug Development at Alfa Cytology: Transforming Cancer Research

The services tend to accelerate the discovery and optimization of molecule drugs with a strict quality control system. ...

ByAlfa Cytology


Differential Gene Expression (DGE) Analysis in RNA Sequencing

Differential Gene Expression (DGE) Analysis in RNA Sequencing

Applications of DGE Analysis Disease Biomarker Discovery: Identification of DEGs between healthy and diseased tissues unveils potential diagnostic or prognostic biomarkers. These biomarkers aid in disease classification, patient stratification, and the development of targeted therapies, paving the way for precision medicine. ...

ByCD Genomics


Analysis of Differential Gene Expression (DGE) in RNA Sequencing

Analysis of Differential Gene Expression (DGE) in RNA Sequencing

Applications of DGE Analysis Disease Biomarker Discovery: Identifying DEGs between healthy and diseased tissues reveals potential diagnostic or prognostic biomarkers. These biomarkers assist in disease classification, patient stratification, and the development of targeted therapies, thereby paving the way for precision ...

ByCD Genomics


Protein Quantification Techniques and Their Application in Clinical Research

Protein Quantification Techniques and Their Application in Clinical Research

LFQ is frequently used to search tumor biomarkers in clinical studies, as tumor adjacent or normal tissues are often treated as control group. de Oliveira et al. found that MMP-7 was presented as a more promising biomarker associated with useful assays of clinical practice for gastric adenocarcinoma patient diagnosis via LFQ results. ...

ByCreative Proteomics


RNA Sequencing Increases the Chance of RNA Biomarker Discovery

RNA Sequencing Increases the Chance of RNA Biomarker Discovery

RNA, not only an essential part of the central dogma, is certainly a relatively untapped resource for biomarker discovery of various diseases. Cumulating data shows that RNA molecules, including mRNAs, lncRNAs, miRNAs, siRNAs, piRNAs, snoRNAs, and snRNAs, are more sensitive and specific than protein biomarkers since they are easy to detect and ...

ByCD Genomics


Betting big on quantitative neurobiomarkers

Betting big on quantitative neurobiomarkers

Introducing Beacon Biosignals: a neurotechnology company founded to develop machine learning-enabled EEG neurobiomarkers and accelerate precision medicine for any disease state affecting the brain Founded by MD/PhDs and engineers from Harvard and MIT, Beacon is propelled by the vision of a computing platform designed to scale the interrogation of large brain datasets with unprecedented ...

ByBeacon Biosignals, Inc.


Lipidomics in Microbial Research

Lipidomics in Microbial Research

The following are examples that applied lipidomics to microbiological research. Discovery of biomarkers Multiple stress responses in microorganisms are accompanied by disordered lipid metabolism. The search for lipid biomarkers is important for the study of microorganisms. Drug targets and applications in new drug development Many researchers ...

ByCreative Proteomics


The power of autoantibodies to enhance clinical development success in Systemic Sclerosis (SSc)

The power of autoantibodies to enhance clinical development success in Systemic Sclerosis (SSc)

NavigAID SSc has been developed using the ImmunoINSIGHTS SeroTag process: Oncimmune’s proprietary biomarker discovery engine. This diagnostic ‘magnifying glass’ helps in understanding the molecular basis of complex autoimmune diseases. ...

ByOncimmune Holdings PLC


Harnessing the utility of autoantibodies to overcome challenges associated with clinical development in Systemic Lupus Erythematosus (SLE)

Harnessing the utility of autoantibodies to overcome challenges associated with clinical development in Systemic Lupus Erythematosus (SLE)

(Roche) is also used as an off-label treatment. The ImmunoINSIGHTS SeroTag biomarker discovery engine can aid in understanding the molecular basis of complex autoimmune diseases. ...

ByOncimmune Holdings PLC

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