Bone Marrow Articles & Analysis: Older
47 articles found
Posterolateral Rabbit Spinal Fusion Study I. Introduction Autologous bone has long been the gold standard for bone graft substitute in spinal fusion procedures. The limited supply and morbidity associated with using autologous graft material led to the development of alternative bone grafting materials. Bioactive glass has a long history of biomedical use and has been shown to facilitate mineral ...
Taking B-cell sequencing as an example, although 2-3% of the B-cells in the peripheral blood come from the bone marrow and spleen, this part of the cells only accounts for a very small part of the entire B-cell population. ...
Background CellRight Technologies® has developed ACTIGEN™ Verified Inductive Bone Matrix, a dehydrated, verified inductive matrix that may be hydrated with saline, blood, Bone Marrow Aspirate (BMA), Platelet Rich Plasma (PRP), or other cellular components in accordance with a physician’s well-informed medical judgment. ...
Anti-anemia APIs Anti-anemia APIs are a class of compounds that can supplement special hematopoietic components or stimulate bone marrow function for the treatment of anemia. According to different types of anemia, anti-anemia APIs are divided into iron preparations for the treatment of iron deficiency anemia (hypochromic anemia) caused by chronic blood loss, ...
Tissue grafts Due to its good biocompatibility, bioactivity and degradability, collagen has been widely studied as a tissue graft. For example, it can be used as bone repair material, tendon repair material, vascular stent and so on. ...
MSCs exhibit specific morphology, which makes them unique compared to other cell types typically used in CLD. While forming spindle-shaped, elongated, and transparent cell projections, the MSCs can pose a significant challenge when it comes to imaging and subsequent image analysis. Many imaging systems on the market are simply not fit for precise detection of these unusual cell types. ...
Hematopoiesis: Cytokines regulate the production and maturation of blood cells in the bone marrow. They stimulate the proliferation and differentiation of hematopoietic stem cells into various blood cell lineages. ...
It has been reported that LNPs loaded with siRNA can be systematically delivered to the bone marrow, but passive diffusion still presents a challenge for bone-targeted drug delivery. ...
They were initially identified in the bone marrow, but have since been found in various other tissues including adipose tissue, peripheral blood, cord blood, fallopian tube, and fetal liver and lung. ...
Introduction to OsteoporosisOsteoporosis is a systemic multi-causal skeletal disease that is prone to fractures due to changes in systemic bone mass and microstructure of bone tissue, resulting in increased bone fragility. ...
It also has an inhibitory effect on hematopoiesis of bone marrow precursor cells. Other studies suggest that IL-17D is associated with viral and tumor diseases, especially through the recruitment of natural killer cells (NK cells). ...
IL-36 beta can activate M2-like macrophages and Langerhans cells; in bone marrow dendritic cells, IL-36 stimulation leads to increased production of pro-inflammatory cytokines (such as IL-1β, IL-6, IL-12, IL-23, and TNF), which may drive innate and adaptive immune responses. ...
The clinical sample types generally include fresh or frozen tissue that often yield high quality DNA and samples that often yield low quantity and/or compromised quality DNA like FFPE (formalin-fixed paraffin-embedded) tissue, decalcified FFPE tissue, bone marrow trephines, smears, and fine needle aspirates (FNA), plasma, and circulating tumor cells. ...
There are a ton of practical uses for computer vision at present times. One industry where this technology is increasingly useful in healthcare. It is impossible to exaggerate the value of computer vision services in the medical field. Its methods continue to be used more widely since they have demonstrated excellent utility in numerous medical contexts, including surgical planning and medical ...
Multiple myeloma (multiple myeloma, MM) is a malignant tumor originating from the B cell lineage, characterized by the clonal proliferation of malignant plasma cells in the bone marrow microenvironment, causing fractures and bone marrow failure, and is the second most common blood system disease in the world Tumors cannot be ...
To avoid the drawbacks of osteochondral autograft transfer, a cylindrical osteoperiosteal graft harvested from the iliac crest covered by a same-sized cylinder of hyaluronic acidebased polymer scaffold pretreated with bone marrow aspirate concentrate and transferred to the chondral defect recipient site in the exact size for restoration of the subchondral ...
Although it is clear that LLPCs preferentially originate in germinal centers (GCs) and relocate to survival niches in bone marrow where they can persist for decades, the issues of the timing of LLPC recruitment and the basis of their retention remain uncertain. Here, using a genetic timestamping system in mice, we show that persistent PCs accrue in ...
For example, when she accompanies her husband to blood transfusion centers, she walks the halls and speaks to patients who are hesitant to receive bone marrow transplants. She listens to them, helps guide them and is a true testament to us all that a full life beyond a cancer diagnosis is possible. ...
It is important to control adipocyte formation to help improve metabolic health and delay aging. Some tissues, such as bone marrow and muscle, accumulate fat over time, which has a negative impact on their function. ...
Also, HLA plays a crucial role in transplants such as organ and bone marrow transplant and is associated with serious adverse reactions to many drugs. ...