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Bone Marrow Articles & Analysis: This-Year
6 articles found
The mature ELANE enzyme is synthesized as a zymogen during neutrophil development and undergoes proteolytic activation and granule packaging within promyelocytes in the bone marrow. Its substrate specificity includes elastin, collagen, fibronectin, laminin, and various microbial proteins. ...
CXCL12, also known as stromal cell-derived factor 1 (SDF-1), is highly expressed in organs like the lungs, liver, and bone marrow—common destinations for metastatic cells. Tumors expressing high levels of the CXCR4 receptor are drawn toward these CXCL12-rich environments. ...
The blood circulation contains platelets as the second most abundant blood cell which perform multiple functions and present themselves as ideal drug carriers. The bone marrow megakaryocytes generate platelets that they release into the blood as cells without nuclei. ...
Human mesenchymal stem cells (hMSCs) are a remarkable type of stem cell found in various tissues, such as bone marrow, adipose tissue, and umbilical cord. These cells have garnered significant attention in the field of regenerative medicine and therapeutic research due to their unique properties and potential applications. ...
Platelet Membrane in Bionic Nanomedicine Platelets are little fragments of cytoplasmic material secreted from the cytoplasm of mature megakaryocytes in mammalian bone marrow. While platelets make up just between 0.5% and 1% of the total blood cells, they're central to body hemostasis. ...
Leukemia, a malignant disorder of the blood and bone marrow, poses significant challenges to both patients and healthcare providers. ...