Breast Tumor Articles & Analysis
19 articles found
The IP10-loaded platelets targeted and inhibited tumor cells in the B16F10 melanoma model and lessened immunosuppressive regulatory T cell activity through CD40L activation on platelet membranes which led to boosted anti-tumor immunity. ...
Among the most promising strategies in this endeavor are the use of tumor models for breast cancer and the development of customized antibody-drug conjugates (ADCs). ...
With professional knowledge of PC (particularly intra-tumor heterogeneity, TME crosstalk, and micro-environmental instability) and powerful cross-platform collaboration capability, Alfa Cytology has launched a series of PC vaccine development services to meet pre-clinical research needs. ...
It is a transmembrane glycoprotein expressed in normal tissues and many epithelial tumors, including breast, cervical, colorectal, esophageal, gastric, and lung cancers. ...
In recent years, further research on MMP-3 has revealed its association with conditions such as glioma, ocular tumors, breast cancer, gastric cancer, non-small cell lung cancer, liver cancer, and even COVID-19. ...
TSLP and TH2 In allergic inflammation, TSLP can strongly activate DCs (dendritic cells), which subsequently drive the development of naive TH cells into "inflammatory" effector TH2 cells that express classical TH2 cytokines, pro-inflammatory tumor necrosis factor-alpha (TNF-α), and anti-inflammatory IL-10. ...
Breast cancer is the malignant tumor with the highest morbidity and mortality among women worldwide. ...
Femtech World featured our partnership with PathPresenter to distribute the 4D Q-plasia OncoReader Breast within PathPresenter’s ClinPx Clinical Workflow Platform in their magazine. ...
Currently, ADC has played a significant role in the treatment of some malignant tumors, such as trastuzumab in the treatment of breast cancer, but its application in the treatment of prostate cancer (PCa) progress slowly. ...
The digital pathology software company PathPresenter (Montville, New Jersey) and the precision oncology platform firm 4D Path have entered into a partnership that could improve the diagnostic accuracy of breast tumor profiling. PathPresenter has developed a digital workflow tool for clinicians, pathologists and pharma companies to aggregate medical data. ...
Recently, an article titled " MAPK4 promotes triple negative breast cancer growth and reduces tumor sensitivity to PI3K blockade" was published in Nature Communications. ...
Clinicians can make better diagnostic and treatment decisions using the data obtained by next-generation sequencing (NGS) technologies. Breast cancers, for example, have typically been diagnosed using mammography, physical exam, and histology. ...
Advances in DNA sequencing technology have made it possible to extensively analyze the breast tumor genome and construct a catalog of gene mutations that may initiate or drive tumor progression. ...
Despite breast cancer being the second most common cancer for women in the US, progress in the breast imaging space has been stagnant over the last few decades. ...
More recently, we have successfully expanded applications of the VeraForm continuous marker beyond breast conserving surgery. One such usage has been the successful deployment of VeraForm during mastectomies where the tumor extended to the chest wall. ...
Ionising radiation is an established etiological agent for breast cancer, but is also a therapeutic modality used in cancer treatment. The accumulation of deoxyribonucleic acid (DNA) damage and deficient DNA repair are considered susceptibility factors that predispose individuals to breast cancer development. In the present study, the genetic damage induced by gamma radiation and repair capacity ...
Reactivation of the ZBP1 gene has been reported in various human tumors. In this study, we identified a detailed molecular mechanism of ZBP1 transactivation in breast cancer cells. ...
Moreover, the transcript is stabilized in breast cancer cells and overexpressed in human breast tumors. Finally, knockdown experiments showed that, in humans, 91H, rather than affecting H19 expression, regulates IGF2 expression in ...
Here, the crossing of ApcMin with cyclin D1–/– mice reduced the intestinal tumor number in animals genetically heterozygous or nullizygous for cyclin D1. Decreased tumor number in the duodenum, intestines, and colons of ApcMin/cyclin D1+/– mice correlated with reduced cellular proliferation and increased differentiation. ...