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Metabolic Health and Disease Research Alterations in NAD/NADH levels are associated with a wide range of diseases, including cancer, diabetes, neurodegenerative disorders (e.g., Alzheimer’s and Parkinson’s), and mitochondrial diseases. ...
This process enables researchers to identify compounds that can modulate receptor activity, which is particularly relevant in the treatment of various diseases, including cancer, diabetes, and cardiovascular disorders. By observing the effects of different compounds on nuclear receptors, scientists can gain insights into the mechanisms of disease and develop ...
Glycan Profiling in Disease Diagnosis Glycan microarrays are increasingly being used for glycan profiling in disease diagnosis, particularly in cancer and infectious diseases. Changes in the glycosylation patterns of proteins and lipids are known to play a significant role in tumor progression and pathogen-host interactions. By analyzing glycan expression profiles, researchers ...
Secretome field can be used to study the regulation and interaction of these pathways.Functional AnalysisThe secretome field also involves understanding the biological functions of secreted proteins, such as how they mediate cell communication, participate in immune responses, regulate metabolism, and affect disease progression.Disease ResearchSecreted proteins are related to many diseases, such ...
Moreover, glycoproteins are involved in the onset and progression of many diseases, such as cancer, diabetes, neurodegenerative diseases, etc.What Is the TAP Detection ...
Furthermore, changes in the mitochondrial proteome may be associated with certain diseases, including neurodegenerative diseases, cancer, heart disease, diabetes, and genetic disorders.Methods of Mitochondrial Protein SequencingMitochondrial protein sequencing typically involves the following steps: firstly, scientists need to extract the mitochondria from cells ...
Dysregulation of sugar nucleotide metabolism has been implicated in a number of diseases, including cancer, diabetes, and congenital disorders of glycosylation. In these conditions, the altered availability of specific sugar nucleotides can lead to the synthesis of aberrant glycans with impaired function. ...
Disturbances in metabolic pathways can lead to many common human diseases such as cancer, diabetes, obesity, hypoglycemia, hypolipidemia, phenylketonuria, neurodegeneration, etc. ...
For instance, altered metabolite profiles have been associated with cancer, diabetes, cardiovascular diseases, and neurodegenerative disorders. ...
In medicine, understanding carbohydrate synthesis is essential for developing treatments for diseases such as diabetes and cancer. In biotechnology, carbohydrate synthesis is used to produce valuable compounds, such as antibiotics and vaccines. ...
GPCRs play a central role in a plethora of biological processes and are linked to a wide range of therapeutic areas including cancer, diabetes, inflammation, cardiovascular diseases, and chronic pain. ...
Many cell and gene therapy solutions have shown considerable promise as a source of possible treatments for a wide range of chronic disorders. However, these sophisticated therapies introduce additional barriers such as the requirements for ultra-low and cryogenic storage, which affect numerous steps of the biomedical solutions’ life cycles, from their development to their administration. ...
In addition, CPPs also play a significantly important role in the delivery of imaging agents, due to their excellent permeability, high affinity, and high stability, with potential applications in the diagnosis and therapy of diseases such as cancer, inflammation, diabetes, central nervous system diseases, and otologic and ocular disorders. ...
Since mitochondria play an important role in the maintenance of homeostasis, their abnormal function is associated with many human diseases, such as neurodegenerative diseases, cancer, heart disease and diabetes. Mutations in more than 350 genes of mitochondrial and nuclear origin have been reported, resulting in mitochondrial diseases. ...
As countries worldwide start relaxing rules and lifting coronavirus restrictions, including wearing face masks in public, people with a weakened immune system may still need to protect themselves against airborne viruses and benefit from cleaner, purified air. ...
As a result, the analysis of proteins and peptides and their post-translational modifications is particularly important for the study of diseases where multiple genes are known to be involved, such as heart disease, cancer, and diabetes. ...
Damage to tissues can result from injuries like burns or wounds, or chronic illnesses like cancer or diabetes. In the body, cells that make up tissues are connected by a matrix, which provides a scaffold support and facilitates cell communication and nutrient exchanges. ...
The WHO report presents the latest data and in-depth analysis for the key areas outlined in the health SDGs: reproductive, maternal, newborn, child and adolescent health; infectious diseases including HIV, tuberculosis, malaria, hepatitis and neglected tropical diseases; noncommunicable diseases (NCDs) including heart disease, cancer and diabetes; mental ...
This article discusses the need for nanotechnology-based drug delivery systems, their advantages, applications and limitations of such drug delivery systems in the treatment of cancer and diabetes.Keywords: nanotechnology, drug delivery systems, cancer, diabetes, gene therapy, nanoparticles, pharmacotherapeutics, disease ...