Cancer Stem Articles & Analysis
4 articles found
Understanding Disease Pathways: As they enable the visualisation of biological processes in cells, reporter lentiviruses are instrumental in studying disease progression and the mechanisms of various illnesses, including cancer. Stem Cell Research: Reporter lentiviral particles are used to label stem cells, thus facilitating the study of ...
CD73 is also implicated in drug resistance, epithelial-to-mesenchymal transition (EMT), and the proliferation and stemness of cancer cells[12]. Tumors also exhibit slower growth in mice lacking A2BR or when treated with A2BR antagonists. ...
In the study, the clinically approved anti-tumor drug doxorubicin was selected as the validation object, which confirmed that the "exosome nanoperforator" could efficiently load it into the exosome, and the drug-loaded exosome could transport doxorubicin into lung cancer cells and tumor spheres, induce cancer cell death and inhibit tumor sphere growth. ...
Stem Cell and Cancer Research Institute, McMaster University Hamilton, CA L8N 3G5; Department of Biochemistry and Biomedical sciences, Faculty of Health Sciences, McMaster University, Hamilton, CA L8N 3G5; Kings College Medical School, Breast Cancer Biology Lab, 3rd floor Thomas Guy House, Guys Hospital, London SE1 ...