Carcinoma Cancer Articles & Analysis
10 articles found
The two antigen-binding arms respectively bind to two antigens on the surface of cancer cells, which can effectively enhance the binding specificity and targeting of the antibody to cancer cells and reduce side effects such as off-target. ...
It is a transmembrane glycoprotein expressed in normal tissues and many epithelial tumors, including breast, cervical, colorectal, esophageal, gastric, and lung cancers. In NSCLC, high Trop-2 expression was observed in 64% of adenocarcinomas and 75% of squamous cell carcinomas (SqCCs). ...
The antibody can be released to partially target and attach to HER2 on cancer cells, and upon entering the cancer cells, release chemotherapeutic drugs to kill the cancer cells as well as nearby cells. ...
In Sun’s research, label-free quantification was applied to systematically compare the protein profiling in saliva and serum exosomes from healthy subjects and lung cancer patients, and potential candidates were discovered as biomarkers for lung cancer. ...
EBV infection is associated with a variety of human malignancies and malignant tissue proliferative diseases, including malignant lymphoma, gastric cancer, nasopharyngeal carcinoma, and hemophagocytic syndrome. Life-cycle of Epstein-Barr Virus. ...
These TACAs have shown potential applications in cancer immunotherapy strategies in past decades. Glycans can serve as a source for the development of novel clinical biomarkers that provide a range of specific targets for therapeutic intervention. ...
NEW YORK - Spanish cancer research firm Universal Diagnostics is gearing up to commercialize a liquid biopsy test that applies methylation biomarkers to detect lung cancer, based on data presented at the International Association for the Study of Lung Cancer 2020 World Conference for Lung Cancer (WCLC) last month. ...
The surgical and radiation oncology team at Providence Mission Hospital (Mission Viejo, Ca) elected to use a novel tumor bed marker called VeraForm for a sarcomatoid carcinoma. Led by James Bredenkamp, M.D. and Quang Luu, M.D., this patient received a VeraForm marker when the lesion was surgically removed, representing a first of its kind for head and neck cancer ...
Subjects who met any of the following criteria were excluded: (1) hepatitis B or C virus infection; (2) autoimmune hepatitis, primary biliary cholangitis or primary sclerosing cholangitis; (3) gastrointestinal cancers or hepatocellular carcinoma; (4) drug-induced steatosis or liver injury; (5) Wilson disease or hemochromatosis; (6) excessive alcohol consumption ...
The purpose of this case study is to highlight ways in which medical algorithms can be integrated into the clinical decision making process. This case study is the first of a series focused on sepsis, a common but complex clinical problem. Use of algorithms can help healthcare providers diagnose sepsis early. Throughout our discussion, appropriate algorithms are suggested to help clinicians ...