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Carcinoma Colorectal Articles & Analysis

2 articles found

Understanding Caco-2 Permeability Assay: A Critical Tool for Drug Development

Understanding Caco-2 Permeability Assay: A Critical Tool for Drug Development

Background of Caco-2 Cells Caco-2 cells are derived from human colorectal carcinoma and possess characteristics that mimic intestinal epithelial cells. ...

ByCreative Bioarray


Cyclin D1 Genetic Heterozygosity Regulates Colonic Epithelial Cell Differentiation and Tumor Number in ApcMin Mice

Cyclin D1 Genetic Heterozygosity Regulates Colonic Epithelial Cell Differentiation and Tumor Number in ApcMin Mice

Constitutive ß-catenin/Tcf activity, the primary transforming events in colorectal carcinoma, occurs through induction of the Wnt pathway or APC gene mutations that cause familial adenomatous polyposis. ...

ByAmerican Society for Microbiology (ASM)

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