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Cardiomyocyte Cell Articles & Analysis

6 articles found

Characterization of Induced Pluripotent Stem Cells (iPSCs)

Characterization of Induced Pluripotent Stem Cells (iPSCs)

Induced pluripotent stem cells (iPSCs) have revolutionized the field of regenerative medicine and cellular biology. They are derived from somatic cells that have been genetically reprogrammed back into an embryonic-like pluripotent state. ...

ByCreative Bioarray


Understanding Induced Pluripotent Stem Cell Differentiation and the Role of iPSC Differentiation Kits in Biological Research

Understanding Induced Pluripotent Stem Cell Differentiation and the Role of iPSC Differentiation Kits in Biological Research

Pluripotent stem cells — cells with the ability to differentiate into nearly any cell type in the body, constituting a significant potential for regenerative medicine. Among these, induced Pluripotent Stem Cells (iPSCs), in particular, have garnered substantial interest from the scientific community due to their ability to ...

ByCreative Bioarray


Predicting cardiotoxicity with engineered 3D human cardiac tissue models

Predicting cardiotoxicity with engineered 3D human cardiac tissue models

The iPSC’s capacity to yield large numbers of pluripotent cells able to differentiate into almost any somatic cell type is attractive. ...

ByInvivoSciences, Inc. (IVS)


Everything You Want to Know About Lipoprotein Lipase

Everything You Want to Know About Lipoprotein Lipase

Lipoprotein lipase (LPL) is a glycoprotein synthesized and secreted by parenchymal cells such as adipocytes, cardiomyocytes, skeletal muscle cells, mammary cells, and macrophages, with a molecular weight of 60ku and containing 3-8% carbohydrates. ...

ByCreative Enzymes


Protein PPARd Can Induce Rapid Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes

Protein PPARd Can Induce Rapid Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes

In a new study, researchers from the Icahn School of Medicine at Mount Sinai have developed a reproducible and scalable method to advance the maturation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs), and hPSC-CMs produced by human stem cell lines in the laboratory support myocardial contraction, which will improve methods for ...

ByCreative BioMart


Gata4 is a direct transcriptional activator of cyclin d2 and cdk4 and is required for cardiomyocyte proliferation in anterior heart field-derived myocardium

Gata4 is a direct transcriptional activator of cyclin d2 and cdk4 and is required for cardiomyocyte proliferation in anterior heart field-derived myocardium

In addition to its role in cardiac differentiation, GATA4 is also required for cardiomyocyte replication, although the transcriptional targets of GATA4 required for proliferation have not been previously identified. ...

ByAmerican Society for Microbiology (ASM)

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