Chemotherapy Drug Articles & Analysis
12 articles found
Precise and safe delivery of drugs to target sites has always been an important task for researchers in modern medicine. ...
The classification of anti-tumor APIs often falls into four main types: chemotherapy drugs, targeted therapy drugs, immunotherapy drugs, and hormone therapy drugs. Each of these targets the malignancy through different mechanisms, offering multiple ways to tackle the disease. Chemotherapy APIs ...
In order to more effectively deliver chemotherapy drugs, Small Molecule Drug Conjugates (SMDC), Antibody Drug Conjugates (ADC), and Degradation Antibody Conjugates (DAC) have been successively explored and developed, enhancing the therapeutic index while providing selective delivery. ...
Loading the liposomes There are two main ways to load drugs into liposomes: Passive loading: This involves mixing the drug with the phospholipids during liposome formation. Hydrophilic drugs stay in the aqueous core, while hydrophobic drugs integrate into the lipid bilayer. ...
The FDA granted Verzenio “breakthrough therapy” status in 2015, and then received Eli Lilly’s New Drug Application on May 5, 2017, followed by Verzenio priority review status on July 10, 2017. ...
Dertrastuzumab is an antibody-drug conjugate (ADC) drug consisting of a humanized monoclonal antibody targeting HER2 attached to a topoisomerase 1 inhibitor payload via a tetrapeptide cleavable linker. ...
Drug development is a balancing act between ensuring that the drug is suitable for the target and that the drug can penetrate the cell membrane to reach the target. ...
CASE PRESENTATION A 70-year-old female recently diagnosed with metastatic pancreatic cancer presented with acute new onset of lower back pain. The patient was taking chemotherapy, participating in a drug therapy trial, and had received radiation therapy. ...
The key to this patient's recovery was a blood stem cell transplant: The researchers first used chemotherapy drugs to kill the patient's own immune cells and then transplanted new cells that would not be infected by HIV. ...
Researchers also believe that there is a link between some types of cardiomyopathy and excessive exposure to certain toxins and/or drugs, such as alcohol, heavy metals and chemotherapy drugs. Symptoms and Diagnosis Unfortunately, pediatric cardiomyopathy often goes undetected until the late stages of the disease when heart failure symptoms ...
In recognition of the International Day of Persons with Disabilities, we hear from one of our #SEGreatPeople on their experience of life with a ...
There is little if any information on appropriate dosing, let alone the efficacy or safety of CBD. Recently, the U.S. Food and Drug Administration (FDA) issued warning letters to 15 companies for illegally selling products that contain CBD in ways that violate the Federal Food, Drug, and Cosmetic Act (FD&C Act). ...