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Chronic Renal Failure Articles & Analysis
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Matrix Gla Protein (MGP) is a small, vitamin K-dependent extracellular matrix protein that plays a critical role in the regulation of vascular calcification and bone development. As a natural inhibitor of pathological mineralization, MGP has attracted significant attention in cardiovascular and skeletal biology research. The development of recombinant MGP protein has enabled researchers to study ...
The study of cardiovascular biology is essential for understanding the mechanisms that regulate heart function and vascular health. As cardiovascular diseases remain the leading cause of death worldwide, advancements in this field offer crucial insights for developing new treatments and preventive strategies. Understanding the Cardiovascular System The cardiovascular system comprises the heart, ...
Structure of Matrix Metalloproteinase (MMP) Family In vertebrates, the MMP family consists of 28 members, at least 23 of which are expressed in human tissues, 14 of which are expressed in the vascular system. MMPs are usually classified into collagenases, gelatinases, stromelysins, matrilysins, membrane-type (MT)-MMPs, and other MMPs based on their substrates and the organization of their ...
GLP-1 agonists and SGLT-2 inhibitors in combination with or without metformin (as required for glycemic management) have also been recommended by multiple guidelines as appropriate initial treatment for type 2 diabetes patients with atherosclerotic cardiovascular disease (ASCVD) or those at high risk for ASCVD, heart failure and/or chronic kidney disease. So, can ...
Overview What is HFpEF? Heart failure with preserved ejection fraction (HFpEF) is a clinical syndrome in which patients have signs and symptoms of HF as the result of high left ventricular (LV) filling pressure, despite normal or near-normal LV ejection fraction (EF). Most patients with HFpEF also display normal LV volumes and an abnormal diastolic filling pattern (i.e, diastolic ...
Muscle loss / muscle wasting is the condition in which, proteolytic systems for protein degradation are activated, while protein synthesis decreases, thereby resulting in muscle fiber shrinkage. This condition may be due age or might be due some chronic conditions like Diabetes mellitus (DM) or chronic kidney disease (CKD). Extreme muscle wasting often results in weight loss. Such a condition is ...
Mice kidney samples are used to study renal biology covering topics such as acute kidney injury to chronic kidney disease, both of which are extremely useful for better understanding renal failure in humans. ...
As we begin this New Year we have an opportunity to begin with a fresh start as we pursue our passion to promote and speed the healing of wounds! Our role as Wound Care Clinicians has risen to a whole new level of essential care for an extremely high risk population. In this current Covid-19 climate that we are living in, we are all facing challenges that we have never dealt with before. ...
Around 37 million people in the United States and around 700 million people worldwide have chronic kidney disease which require patients to utilize dialysis centers. These dialysis clinics provide lifesaving treatments to the patients that need them. While having any medical procedure performed, communication between the healthcare provider and the patient is vital to ...
They may have a lot of comorbidities—such as diabetes, chronic kidney disease, end-stage renal disease—and they’re complex cases. ...
After seven years and 5,300-patients tested, the results of the landmark TAILOR-PCI trial were announced in a virtual ACC session. This trial investigated whether a prospective approach using rapid on-site CYP2C19 testing could improve patient outcomes when selecting P2Y12 inhibitor therapy following PCI procedure. This is based on the well-established evidence that approximately 30-50% of ...
And now to a story that is never far from the headlines. If is about an EPA – Registered herbicide that has been linked to kidney disease. This story demonstrates the extent that entities will go to protext their commercial interests. The story comes from the organisation Beyond Pesticides. (Beyond Pesticides, February 6, 2019) The American Association for the Advancement of Science (AAAS) ...
Among the exclusion criteria were chronic obstructive pulmonary disease, renal failure, bleeding disorders, pulmonary hypertension, antiarrhythmic drugs, and antibiotics. ...
A rigorous and consistent set of outcomes definitions for hemodialysis access are necessary to clarify factors contributing to fistula success and the clinical consequence of fistula failure. Keywords: Arteriovenous fistula, Haemodialysis, Patency, Maturation, Meta-analysis Introduction The use of chronic haemodialysis (HD) as renal ...
This case study discusses hospital readmissions and provides healthcare professionals with recommended medical algorithms in the form of scores, models, and calculators that can aid in reducing readmissions, especially when related to antibiotic resistant microbiological pathogens. When health analytics, such as the CDC antibiotic resistance program and other algorithms are integrated into ...
According to the BOP, “certain risks and conditions, such as HIV infection, diabetes, chronic renal failure, injection drug use history, and close contact with someone who is sick with infectious TB, all pose a greater risk for getting TB ...
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