- Home
- Articles
- latamerica
- clinical development
Refine by
Clinical Development Articles & Analysis
103 articles found
This approach has gained rapid attention across academia, biotech, and big pharma. Clinical Progress Preceding Academic Validation Interestingly, clinical development in in vivo CAR-T advanced before large-scale academic confirmation was published. In June 2025, Capstan Therapeutics announced the initiation of a Phase I clinical ...
For centuries outbreaks of numerous diseases called pandemics would plague human populations in large regions or even world-wide. Throughout history there have been a number of widespread pandemics the most devastating being the Black Death pandemic that killed over 75 million people in the 1350’s and the latest being influenza outbreaks, also known as the Spanish flu, in 1918 and ...
Regulatory Compliance: Navigating the complex landscape of FDA regulations for radioactive materials is crucial. Development services help ensure that all necessary compliance requirements are met before clinical trials can commence. ...
Preclinical drug discovery represents a critical phase in the development of new therapeutics. It is the process that bridges the gap between basic research and clinical testing, allowing for the evaluation of potential drug candidates in biological systems before they are tested in humans. ...
Additionally, multiplex cytokine analysis is a valuable tool in vaccine development and drug discovery, providing real-time feedback on immune modulation. ...
One of the primary uses is in drug testing and development. Researchers utilize these cell lines to screen potential therapeutic agents, examining their effectiveness in inhibiting cancer cell growth. This screening process helps identify promising candidates for further development into clinical treatments. In addition to drug testing, ...
Recombinant protein drugs refer to protein products that originate from animals and plants and are developed through biotechnology research. These protein drugs exhibit certain biological activity and can prevent, diagnose, and treat diseases in humans, animals, and plants. ...
Currently, there are more than 160 PROTAC projects under development worldwide, of which nearly 20 projects are in clinical development. ...
Medical advancement relies on clinical trials, which are essential for the development of safe and effective innovative treatments. ...
They have the advantages of small size, high stability, and good penetration, and therefore have a wide range of application prospects in the fields of clinical treatment, diagnostic reagent development, etc.Characteristics of NanobodiesThe size of nanobodies usually ranges between 10-15kDa, which is only 1/10 of the size of regular antibodies. ...
Alfa Cytology has announced pancreatic cancer vaccine development services to improve the efficacy and safety of related vaccines. ...
Dr. Kate Sasser from Tempus led a discussion on the potential of antibody-drug conjugates (ADCs), their challenges in targeting tumor antigens, and the future of cancer treatment with Dr. Daniel Johnson, Dr. Funda Meric-Bernstam, and Dr. Kellogg Parsons. The oncology field is rapidly advancing with the development of antibody-drug conjugates (ADCs), offering new hope for ...
ByTempus
In addition, many CDM systems are not user-friendly or interactive, making it difficult for users to get the most out of them. What challenges do clinical data management systems currently face? Clinical Trial Complexity The modern clinical trial design requires real-time data modelling and simulation to provide reliable information that ...
ByClinion
At the same time, pre-clinical studies are also significant to assess the efficacy and safety of small molecule drugs in brain cancer before they enter clinical trials in humans. ...
Currently, RDC drugs have made significant breakthroughs in cancer treatment alongside the development of antibody drugs and ADCs. Antibodies are relatively effective for hematologic malignancies. ...
These bioactive compounds have the potential to be developed into novel medications for the treatment of various diseases. ...
As immune checkpoint tracers for macrophage-infiltrating immune diseases, nanobodies can identify immune response patterns, predict treatment responses, and track the biological processes of immune system activation, thereby improving the effectiveness of immunotherapy. The clinical research targets of nanobodies used for molecular diagnosis include HER2, HER3, PD-L1, AlbudAb, ...
Therefore, there is a need to deepen our understanding of the physical, chemical, and biological properties of these adjuvants to provide a theoretical basis for determining the quality attributes of each adjuvant and selecting the appropriate type of adjuvant as early as possible in the clinical development phase. Type of Aluminum Adjuvants The two main types of ...
Animal models play a critical role in biomedical research, as they allow scientists to study complex disease processes, develop new therapies, and test their safety and efficacy before moving into human clinical trials. ...
Maternal serum samples were collected between 20 and 37 weeks of gestation. Clinical suspicion of preeclampsia was defined as presence of new-onset proteinuria, or clinical symptoms of preeclampsia. Subjects with a clinical diagnosis of preeclampsia at the time of enrollment were excluded. ...