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Abstract Background: Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation of synovial joints. Anticitrullinated protein autoantibodies are detected by the CCP test in early disease and predict the development of erosive disease as well as extraarticular manifestations. We recently reported that many RA patients have anti-citrullinated albumin (ACA) ...
Abstract Background: Preeclampsia is a major pregnancy complication that results in significant maternal and infant mortality, most of which occurs in low and middle-income countries. The accurate and timely diagnosis of preeclampsia is critical in management of affected pregnancies to reduce maternal and fetal/neonatal morbidity and mortality, yet difficulties remain in establishing the rigorous ...
Do you have a patient with Systemic Lupus Erythematosus (SLE) that you suspect may also have Sjögren’s Syndrome (SS)? With shared clinical and serological features, overlapping SS with SLE is a comorbidity that is often challenging to identify to promptly assist clinical management. This may also lead to misdiagnoses of other connective tissue disorders. New data on 14-3-3η (eta) ...
Highlights The depletion of Roseburia is associated with alcohol consumption in human cohorts R. intestinalis ameliorates the experimental ALD in mice regardless of viability Flagellin from R. intestinalis protects on ethanol-disrupted gut barrier functions The ethanol-induced gut microbiota dysbiosis is restored by R. intestinalis Summary Although a link between the gut microbiota ...
Perfluoroalkyl compounds (PFCs) are ubiquitous, persistent chemical contaminants found in the environment, wildlife, and humans. Despite the widespread occurrence of PFCs, little is known about the impact these contaminants have on the health of wildlife populations. We investigated the relationship between PFCs (including Σperfluorocarboxylates, Σperfluoroalkyl sulfonates, perfluorooctane ...