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Colon Cancer Articles & Analysis
26 articles found
Population growth, aging populations and increases in cancer incidence have necessitated new approaches to identifying effective treatments. One such approach involves the repositioning, or repurposing, of drugs already FDA approved in either non-oncology disease states and/or approved in a limited number of tumor types. The repurposing of these drugs for new indications represents an ...
The biological functions of platelets are preserved in platelet micromotors with their ability to target cancer cells and pathogens. Biofuels enable motor-shaped platelet micromotors to achieve directed propulsion. ...
CD BioSciences has launched new services on anti-centrosome antibody development to assist cancer preclinical research. It is committed to providing full packages from antigen synthesis to antibody generation and manufacturing. ...
It is used to treat adult patients with metastatic triple-negative breast cancer (mTNBC) and locally advanced or metastatic urothelial cancer (UC) who have received at least 2 therapies in the past. ...
Relationship Between Immunity, Inflammation and Cancer Immunity is an act of self-protection of the body. The immune response is divided into specific and non-specific. ...
Introduction Genomics has revolutionized cancer research, transforming the way we diagnose, treat, and monitor cancer. ...
In addition to its indirect effects, TSLP can directly act on CD4+ T cells, aiding in their proliferation, differentiation, and response to antigens[3]. TSLP and cancer New functions of TSLP have been discovered in the induction and progression of various tumors, including solid tumors such as breast, colon, and pancreatic cancers, as well as ...
The antibody can be released to partially target and attach to HER2 on cancer cells, and upon entering the cancer cells, release chemotherapeutic drugs to kill the cancer cells as well as nearby cells. ...
So far, studies have found that it has anti-metastasis and anticancer activities, antioxidant, free radical scavenging, hypoglycemic, hypolipidemic and other pharmacological activities, and a large number of experimental results show that its biological activities are better than curcumin, such as antioxidant chloroquine-induced kidney damage, antioxidant azo-methane induced ...
With over 35 years experience, hundreds of published papers and thousands of citations, Professor Satoshi Teramukai's innovative work ranges from a Bayesian predictive sample size design for a single-arm exploratory clinical trial, to designing and implementing SACURA, the only randomized-controlled trial focused on adjuvant therapy for stage II colon cancer. ...
ByStatsol
Background Combination chemotherapy using fluorouracil, leucovorin with or without oxaliplatin (5-FU and FOLFOX) are standard treatment for locally advanced colon cancer. However, about half of the patients developed recurrence. The objective of this study was to use gene profiling to predict treatment efficacy for colon cancer ...
Classification and Functions of Common Phytochemicals Flavonoids Species: Quercetin, brassin, catechin, lignan, anthocyanin, resveratrol Functions: Anti-inflammatory, antibacterial, antioxidant, cancer prevention (breast cancer, ovarian cancer), lowering blood lipids and cholesterol Carotenoids Species: Carotene, lutein, zeaxanthin, ...
During the period, the researchers found that the OR2H1 protein was also expressed in a variety of solid tumors, including 4% of colon cancer samples to 69% of gallbladder cancer samples. Importantly, OR2H1 was only found in the testis of all normal tissues examined, which may suggest that therapies targeting OR2H1 may have little effect on ...
Oncology and autoimmune diseases (rheumatoid arthritis, multiple sclerosis) are currently among the clinical pipeline indications for LAG-3 which acts as an immunomodulator in a variety of tumors, including leukemia, non-small cell lung cancer, colon cancer, pancreatic cancer, and head and neck cell cancer. ...
It is a medication used to treat prostate cancer. It is used in combination with corticosteroid for metastatic castration-resistant prostate cancer (mCRPC) and metastatic high-risk castration-sensitive prostate cancer (mCSPC). ...
Research Achievements of Human Microbiome In recent years, with the continuous research on the human microbiome, gut microbes have been found to be closely related to a variety of human diseases, including not only digestive tract diseases such as colitis and colon cancer (these digestive tract diseases, flora, and digestive tract are in direct contact), but ...
While these cells are of human origin, they were originally derived from a colon cancer tumor and are transformed, which may lead to these cells not having the same physiological responses as healthy intestinal cells. ...
The robot arms move above the patient’s stomach as if guided by an invisible hand. Monitors on each side of the operating table show an oversized, 3-D image of the stomach’s interior. Two meters (about six feet) away, Dr. Markus Mille sits fully absorbed at the control ...
Lack of Robust in Vitro Gut Models Very few in vitro models available accurately represent the gut. Some immortalized or cancerous cell lines, such as Caco-2 cells, are relatively simple to use and enable studies to be conducted fairly quickly. ...
For instance, radiation or chemotherapy treatments for cancer can have significant off-target effects involving intestinal and colonic stem cells, because the gut is one of the first areas of the body negatively affected by these therapies. ...